Vitamin D, traditionally known as an essential nutrient, is a precursor of a potent steroid
hormone that regulates a broad spectrum of physiological processes. In addition to its …

This is a narrative review of the evidence supporting vitamin D's anticancer actions. The first
section reviews the findings from ecological studies of cancer with respect to indices of solar …

Tumor cells undergo senescence in response to both conventional and targeted cancer
therapies. The induction of senescence in response to cancer therapy can contribute to …

In the last two decades, accumulating evidence pointed to the importance of autophagy in
various human diseases. As an essential evolutionary catabolic process of cytoplasmatic …

Breast cancer is the most common cancer among women worldwide, yet successful
treatment remains a clinical challenge. Ivermectin, a broad-spectrum antiparasitic drug, has …

Vitamin D and its active metabolites are important nutrients for human skeletal health. UV
irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the …

Ionizing radiation (IR) has found widespread application in modern medicine, including
medical imaging and radiotherapy. As a result, both patients and healthcare professionals …

H460 non-small cell lung, HCT116 colon and 4T1 breast tumor cell lines induced into
senescence by exposure to either etoposide or doxorubicin were able to recover …

Tumor cells along with a small proportion of cancer stem cells exist in a stromal
microenvironment consisting of vasculature, cancer-associated fibroblasts, immune cells …

Vitamin D regulates the pleiotropic effect to maintain cellular homeostasis and
epidemiological evidence establishes an association between vitamin D deficiency and …