1, 2, 3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships

Z Xu, SJ Zhao, Y Liu - European journal of medicinal chemistry, 2019 - Elsevier
Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …

Synthesis and reactivity of propargylamines in organic chemistry

K Lauder, A Toscani, N Scalacci… - Chemical reviews, 2017 - ACS Publications
Propargylamines are a versatile class of compounds which find broad application in many
fields of chemistry. This review aims to describe the different strategies developed so far for …

[HTML][HTML] 1, 2, 3-Triazole-containing compounds as anti–lung cancer agents: Current developments, mechanisms of action, and structure–activity relationship

T Liang, X Sun, W Li, G Hou, F Gao - Frontiers in pharmacology, 2021 - frontiersin.org
Lung cancer is the most common malignancy and leads to around one-quarter of all cancer
deaths. Great advances have been achieved in the treatment of lung cancer with novel …

Recent advances in synthesis and medicinal chemistry of benzodiazepines

N Arora, P Dhiman, S Kumar, G Singh, V Monga - Bioorganic Chemistry, 2020 - Elsevier
Benzodiazepines (BZDs) represent a diverse class of bicyclic heterocyclic molecules. In the
last few years, benzodiazepines have emerged as potential therapeutic agents. As a result …

[HTML][HTML] An ultrasound assisted, ionic liquid-molecular iodine synergy driven efficient green synthesis of pyrrolobenzodiazepine-triazole hybrids as potential …

M Saquib, S Ahamad, MF Khan, MI Khan… - Frontiers in …, 2023 - frontiersin.org
Herein, we report an efficient and eco-friendly, ultrasound assisted synthetic strategy for the
construction of diversified pyrrolobenzodiazepine-triazole hybrids, which are potentially …

Synthesis of Cu-porphyrazines by annulated diazepine rings with electrochemical, conductance activities and computational studies

AM Fahim, HS Magar, E Nasar, FM Abdelrazek… - Journal of Inorganic and …, 2022 - Springer
In this investigation, we synthesized novel Cu-porphyrazines annulated with diazepines
moiteis, the diazepines rings were obtained via 1, 4-cycloaddition reactions of chalcone …

Design, synthesis, antibacterial evaluation and docking studies of triazole and tetrazole linked 1, 4‐benzodiazepine nucleus via click approach

M Devi, S Jaiswal, N Yaduvanshi, N Kaur… - …, 2023 - Wiley Online Library
Abstract A novel series of 1, 4‐triazole and 1H‐tetrazole pharmacophoric motifs embellished
analogues linked to the privileged 1, 4‐benzodiazepine nucleus through an …

Recent advances in reactions of propargylamines

X Sheng, K Chen, C Shi, D Huang - Synthesis, 2020 - thieme-connect.com
Propargylamines are extremely versatile and common building blocks in the field of
chemistry. This review highlights the recent advances made in the reactions of …

Progress in the Synthesis of Fused 1, 2, 3‐Triazoles

H Kumar, M Dhameja, M Rizvi, P Gupta - ChemistrySelect, 2021 - Wiley Online Library
Fused heterocycles display prodigious prominence in diverse field ranging from medicinal
chemistry to material science and chemical biology to catalysis. Owing to biological …

Design, synthesis, molecular docking, and antibacterial study of aminomethyl triazolo substituted analogues of benzimidazolo [1, 4]-benzodiazepine

M Devi, S Jaiswal, N Yaduvanshi, S Jain, S Jain… - Journal of Molecular …, 2023 - Elsevier
Sternbach-Reeder rearrangement of 2-chloromethyl substituted derivatives of
benzimidazolo annulated analog of quinazoline 4 (ae) with propargyl amine (5) proceeded …