Schizophrenia (SCZ) is a polygenic, complex mental disorder of which a diagnosis is often
made based on psychiatric history and clinical observation with few available objectives and …

Pneumolysin is a major virulence factor of Streptococcus pneumoniae that plays a key role
in interaction with the host during invasive disease. How pneumolysin influences these …

Microglia are thought to play key roles in the progression of Alzheimer disease (AD).
Overactivated microglia produce proinflammatory cytokines, such as tumor necrosis factor-α …

EP4 receptor-associated protein (EPRAP) is a newly identified molecule that regulates
macrophage activation. We recently demonstrated the presence of EPRAP in the mice brain; …

Prostaglandin E2 receptor 4–associated protein (EPRAP) is a key molecule in suppressing
inflammatory responses in macrophages. EPRAP is expressed not only in macrophages but …

The diagnosis of schizophrenia (SCZ) patients largely rely on abnormal behavior and
mental state examination, which is inevitably subjective and susceptible. Finding more …

摘要背景: 外伤性视神经损伤是引起视力丧失的重要原因, 治疗方法也比较局限,
为探求更好的治疗方法, 该实验从小胶质细胞方向入手进行探究. 在神经病理条件下 …

The cholesteryl ester transfer protein (CETP) is a lipid transfer protein responsible for the
exchange of cholesteryl esters and triglycerides between lipoproteins. Decreased CETP …

This study was designed to determine the effect of metformin on the release of inflammatory
factors by lipopolysaccharide (LPS)-stimulated microglia and investigate the mechanisms …

Astrocytes interact closely with neurons via glutamate; this astrocyte-neuron circuit may play
a pivotal role in synaptic transmission. In addition, astrocytes contact vascular endothelial …