Cell death and inflammation are key pathologic responses of acute pancreatitis (AP), the
leading cause of hospital admissions for gastrointestinal disorders. It is becoming …

Sažetak The existence of cell free DNA in the human circulatory system has been known
since the 1950s, however, intensive research in this area has been conducted for the last …

Objectives Extracellular histones are rapidly cleared by the liver and rarely detectable in the
circulation unless there is extensive cell death, as in severe trauma and sepsis. This study …

Background The components of nucleosomes, which contain DNA and histones, are
released into the circulation from damaged cells and can promote inflammation. We studied …

Background Patients with severe acute pancreatitis (SAP) have a high mortality, thus early
diagnosis and interventions are critical for improving survival. However, conventional tests …

Cell-free DNA has been associated with outcome in several acute conditions including two
reports concerning the outcomes after cardiac arrest that found association of circulating …

The number of studies investigating the use of circulating nucleic acids as potential
biomarkers has grown significantly in recent years. The detection of such biomarkers is a …

Objective: To evaluate cfDNA as an indicator of pancreatitis severity. Background: Acute
pancreatitis severity scores have limited proficiency, and are complex and challenging to …

This is a compilation of the reports of the three first quarters of 2010 on what is written in the
scientific literature on pancreas. The main source has been PubMed, but also the Journals …

Background: Critical illness (CI) is a major global health burden and the leading cause of
death in the intensive care unit. It can originate from a wide range of aetiologies and often …