Phytosterols as anticancer compounds

PG Bradford, AB Awad - Molecular nutrition & food research, 2007 - Wiley Online Library
Phytochemicals have been proposed to offer protection against a variety of chronic ailments
including cardiovascular diseases, obesity, diabetes, and cancer. As for cancer protection, it …

Phytochemicals and cancer risk: a review of the epidemiological evidence

PE Miller, DC Snyder - Nutrition in Clinical Practice, 2012 - Wiley Online Library
A number of epidemiological studies have investigated associations between various
phytochemicals and cancer risk. Phytoestrogens and carotenoids are the two most …

Antioxidant-rich natural fruit and vegetable products and human health

AIO Jideani, H Silungwe, T Takalani… - … Journal of Food …, 2021 - Taylor & Francis
Antioxidants are important ingredients that are present in fruits and vegetables (FAV). With
increased consumption of FAV in its raw and processed form, a predominantly plant-based …

Sulfur deficiency–induced repressor proteins optimize glucosinolate biosynthesis in plants

F Aarabi, M Kusajima, T Tohge, T Konishi… - Science …, 2016 - science.org
Glucosinolates (GSLs) in the plant order of the Brassicales are sulfur-rich secondary
metabolites that harbor antipathogenic and antiherbivory plant-protective functions and have …

Covalent binding to tubulin by isothiocyanates: a mechanism of cell growth arrest and apoptosis

L Mi, Z Xiao, BL Hood, S Dakshanamurthy… - Journal of Biological …, 2008 - ASBMB
Isothiocyanates (ITCs) found in cruciferous vegetables, including benzyl-ITC (BITC),
phenethyl-ITC (PEITC), and sulforaphane (SFN), inhibit carcinogenesis in animal models …

Cruciferous vegetables and risk of colorectal neoplasms: a systematic review and meta-analysis

G Tse, GD Eslick - Nutrition and cancer, 2014 - Taylor & Francis
Evidence shows cruciferous vegetables exhibit chemoprotective properties, commonly
attributed to their rich source of isothiocyanates. However, epidemiological data examining …

Effect of cooking brassica vegetables on the subsequent hydrolysis and metabolic fate of glucosinolates

V Rungapamestry, AJ Duncan, Z Fuller… - Proceedings of the …, 2007 - cambridge.org
The protective effects of brassica vegetables against cancer may be partly related to their
glucosinolate content. Glucosinolates are hydrolysed by plant myrosinase following damage …

Mechanisms of action of isothiocyanates in cancer chemoprevention: an update

SL Navarro, F Li, JW Lampe - Food & function, 2011 - pubs.rsc.org
Isothiocyanates (ITC), derived from glucosinolates, are thought to be responsible for the
chemoprotective actions conferred by higher cruciferous vegetable intake. Evidence …

The molecular basis that unifies the metabolism, cellular uptake and chemopreventive activities of dietary isothiocyanates

Y Zhang - Carcinogenesis, 2012 - academic.oup.com
Organic isothiocyanates (ITCs), which are characterized by the presence of an–N= C= S
group, are among the most extensively studied cancer chemopreventive agents and show …

Anticarcinogenic effects of isothiocyanates on hepatocellular carcinoma

Y Zhang, H Huang, L Jin, S Lin - International Journal of Molecular …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer,
accounting for about 90% of cases. Sorafenib, lenvatinib, and the combination of …