The present paper review the drug–DNA interactions, their types and applications of
experimental techniques used to study interactions between DNA and small ligand …

The use of visible light to produce highly selective and potent drugs through photodynamic
therapy (PDT) holds much potential in the treatment of cancer. PDT agents can be designed …

Increasing numbers of DNA structures are being revealed using biophysical, spectroscopic
and genomic methods. The diversity of transition metal complexes is also growing, as the …

The design of small complexes that bind and react at specific sequences of DNA becomes
important as we begin to delineate, on a molecular level, how genetic information is …

For more than 50 years bioinorganic chemistry has remained an expanding and exciting
interdisciplinary field of science. 1-6 One of the rapidly growing and evolving new research …

DNA mismatches represent a novel target in the development of diagnostics and
therapeutics for cancer, because deficiencies in DNA mismatch repair are implicated in …

Biomolecular interactions can be defined by combining thermodynamic data on the
energetic properties of the interaction with high-resolution structural data. The development …

Two complexes of [Co (phen) 2IP] 3+(IP= imidazo [4, 5-f][1, 10] phenanthroline) and [Co
(phen) 2PIP] 3+(PIP= 2-phenylimidazo [4, 5-f][1, 10] phenanthroline) have been synthesized …

This paper presents recent progress in our laboratory on the interaction of Ru (II)/Co (III)
polypyridine complexes with DNA. The first part describes the effect on DNA binding of …

[Ru (phen) 2dppz] 2+(phen= 1, 10-phenanthroline, dppz= dipyridophenazine) and closely
related complexes have previously been observed to have an undetectably small quantum …