Biological roles of adenine methylation in RNA

K Boulias, EL Greer - Nature Reviews Genetics, 2023 - nature.com
Abstract N 6-Methyladenosine (m6A) is one of the most abundant modifications of the
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …

Tuning the ribosome: the influence of rRNA modification on eukaryotic ribosome biogenesis and function

KE Sloan, AS Warda, S Sharma, KD Entian… - RNA biology, 2017 - Taylor & Francis
ABSTRACT rRNAs are extensively modified during their transcription and subsequent
maturation in the nucleolus, nucleus and cytoplasm. RNA modifications, which are installed …

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

JL Woolford Jr, SJ Baserga - Genetics, 2013 - academic.oup.com
Ribosomes are highly conserved ribonucleoprotein nanomachines that translate information
in the genome to create the proteome in all cells. In yeast these complex particles contain …

Evidence for rRNA 2′-O-methylation plasticity: Control of intrinsic translational capabilities of human ribosomes

J Erales, V Marchand, B Panthu… - Proceedings of the …, 2017 - National Acad Sciences
Ribosomal RNAs (rRNAs) are main effectors of messenger RNA (mRNA) decoding, peptide-
bond formation, and ribosome dynamics during translation. Ribose 2′-O-methylation (2 …

Biology of Giardia lamblia

RD Adam - Clinical microbiology reviews, 2001 - Am Soc Microbiol
Giardia lamblia is a common cause of diarrhea in humans and other mammals throughout
the world. It can be distinguished from other Giardia species by light or electron microscopy …

Chemical modifications in the life of an mRNA transcript

S Nachtergaele, C He - Annual review of genetics, 2018 - annualreviews.org
Investigations over the past eight years of chemical modifications on messenger RNA
(mRNA) have revealed a new level of posttranscriptional gene regulation in eukaryotes …

The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA

NJ Watkins, MT Bohnsack - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
Abstract Box C/D and H/ACA RNPs are essential ribonucleoprotein particles that are found
throughout both eukaryotes [small nucleolar RNPs (snoRNPs)] and archaea [snoRNP‐like …

An updated human snoRNAome

H Jorjani, S Kehr, DJ Jedlinski, R Gumienny… - Nucleic acids …, 2016 - academic.oup.com
Small nucleolar RNAs (snoRNAs) are a class of non-coding RNAs that guide the post-
transcriptional processing of other non-coding RNAs (mostly ribosomal RNAs), but have …

rRNA modifications and ribosome function

WA Decatur, MJ Fournier - Trends in biochemical sciences, 2002 - cell.com
The development of three-dimensional maps of the modified nucleotides in the ribosomes of
Escherichia coli and yeast has revealed that most (∼ 95% in E. coli and 60% in yeast) occur …

Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs

Z Kiss-László, Y Henry, JP Bachellerie… - Cell, 1996 - cell.com
Eukaryotic cells contain many fibrillarin-associated small nucleolar RNAs (snoRNAs) that
possess long complementarities to mature rRNAs. Characterization of 21 novel antisense …