Hydrogen–deuterium exchange coupled with mass spectrometry (HDX-MS) is a powerful
technique for the characterization of protein–ligand interactions. Currently, there is a …

Lytic polysaccharide monooxygenases (LPMOs) are copper-containing enzymes which
promote the degradation of recalcitrant polysaccharides like cellulose or chitin. Here, we …

The transmissible locus of stress tolerance (tLST) is a genomic island which confers
resistance to heat and chlorine. In this study, we determined that the tLST is frequent in …

While protein refolding has been studied for over 50 years since the pioneering work of
Christian Anfinsen, there have been a limited number of studies correlating results between …

AAA+ ATPases are ubiquitous proteins associated with most cellular processes, including
DNA unwinding and protein unfolding. Their functional and structural properties are typically …

This study investigates the impact of aromatic–aromatic interactions on the cold adaptation
of thioredoxin (Trx), a small redox protein with a conserved Trx-fold structure. Two Trx …

The locus of heat resistance (LHR) confers resistance to extreme heat, chlorine and
oxidative stress in Escherichia coli. This study aimed to determine the function of the LHR in …

YfdX is a prokaryotic protein encoded by several pathogenic bacteria including Salmonella
enterica serovar Typhi, which causes one of the most fatal infectious diseases, typhoid fever …

The thermomechanical response of Omp2a, a representative porin used for the fabrication of
smart biomimetic nanomembranes, has been characterized using microcantilever …

In Klebsiella pneumoniae CG43S3, deletion of the response regulator gene rcsB reduced
the capsular polysaccharide amount and survival on exposure to acid stress. A comparison …