Combating anti-microbial resistance by developing alternative strategies is the need of the
hour. Cell division, particularly FtsZ, is being extensively studied for its potential as an …

Although many components of the cell division machinery in bacteria have been identified,,
the mechanisms by which they work together to divide the cell remain poorly understood …

Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that causes severe
nosocomial infections in susceptible individuals due to the emergence of multidrug-resistant …

Bacterial cell division is initiated by the assembly of the contraction ring (Z-ring), which
consists of the self-assembled FtsZ protofilaments and dozens of other associate proteins …

Z-ring formation by FtsZ, the master assembler of divisome, is a key step in bacterial cell
division. Both formation and membrane anchoring of the Z-ring requires assistance of a …

Cell division in most bacteria is regulated by the tubulin homolog FtsZ as well as ZapA, a
FtsZ-associated protein. However, how FtsZ and ZapA function coordinately has remained …

The X family polymerases (PolXs) are specialized DNA polymerases that are found in all
domains of life. While the main representatives of eukaryotic PolXs, which have dedicated …

Cells generate more cells. This proliferation requires multiple cellular-scale morphological
changes from one generation to the next. One cell must physically separate into two …