Free radicals or reactive oxygen species (ROS) are generated by oxygen metabolism which
is balanced by the rate of oxidant formation and the rate of oxidant elimination. Oxidative …

Hypertension is considered to be the most important risk factor in the development of
cardiovascular disease. An increasing body of evidence suggests that oxidative stress …

Essential hypertension is a highly prevalent pathological condition that is considered as one
of the most relevant cardiovascular risk factors and is an important cause of morbidity and …

NADPH oxidase-derived reactive oxygen species (ROS) have been reported to activate
NLRP3 inflammasomes resulting in podocyte and glomerular injury during …

Aim: Our previous studies have shown that NOD-like receptor protein (NALP3)
inflammasome activation is importantly involved in podocyte dysfunction and glomerular …

Lipid rafts, the sphingolipid and cholesterol-enriched membrane microdomains, are able to
form different membrane macrodomains or platforms upon stimulations, including redox …

Hypertension is a highly prevalent disease worldwide. It is known for being one of the most
important risk factors for developing cardiovascular disease, including acute myocardial …

Aims: This study hypothesized that activation of endothelial nucleotide oligomerization
domain-like receptor protein with pyrin domain containing 3 (Nlrp3) inflammasomes directly …

Proteinuria is an independent risk factor for end‐stage renal disease (ESRD)(Shankland,
2006). Recent studies highlighted the mechanisms of podocyte injury and implications for …

In our previous study, the clams (Ruditapes philippinarum) were inoculated with Bacillus
natto and fermented to produce peptides (RBPs) with high ACE inhibitory effect in vitro. In …