The pulmonary circulation is a low-resistance, low-pressure, and high-compliance system
that allows the lungs to receive the entire cardiac output. Pulmonary arterial pressure is a …

Abnormal function of suborganelles such as mitochondria and endoplasmic reticulum often
leads to abnormal function of cardiomyocytes or vascular endothelial cells and …

The preimplantation period of embryonic development can be a key window for
programming of postnatal development because extensive epigenetic remodeling occurs …

Chronic hypoxia is a common cause of pulmonary hypertension, preeclampsia, and
intrauterine growth restriction (IUGR). The molecular mechanisms underlying these …

Ca2+ signaling in pulmonary arterial smooth muscle cells (PASMCs) plays an important role
in pulmonary hypertension (PH). However, the underlying specific ion channel mechanisms …

Background As a complication of Type II Diabetes Mellitus (T2DM), the etiology,
pathogenesis, and treatment of cognitive dysfunction are still undefined. Recent studies …

Cardiac hypertrophy has been shown to compensate for cardiac performance and improve
ventricular wall tension as well as oxygen consumption. This compensatory response results …

Pulmonary dysfunction is tightly associated with cough variant asthma (CVA), a respiratory
damage disease. Suhuang antitussive capsule (Suhuang), one of traditional Chinese patent …

Background Isorhapontigenin (ISO) has been shown to have antioxidant activity. This study
aimed to investigate the antioxidant effects of ISO on cerebral ischemia/reperfusion (I/R) …

Mitochondria are important organelles that act as a primary site to produce reactive oxygen
species (ROS). Additionally, mitochondria play a pivotal role in the regulation of Ca2+ …