Tet-mediated DNA demethylation is required for SWI/SNF-dependent chromatin remodeling and histone-modifying activities that trigger expression of the Sp7 …

H Sepulveda, A Villagra… - Molecular and cellular …, 2017 - Taylor & Francis
Here we assess histone modification, chromatin remodeling, and DNA methylation
processes that coordinately control the expression of the bone master transcription factor …

[HTML][HTML] SENP2 suppresses browning of white adipose tissues by de-conjugating SUMO from C/EBPβ

JS Lee, S Chae, J Nan, Y Do Koo, SA Lee, YJ Park… - Cell Reports, 2022 - cell.com
The adipose tissue is a key site regulating energy metabolism. One of the contributing
factors behind this is browning of white adipose tissue (WAT). However, knowledge of the …

Brg1 Controls the Expression of Pax7 to Promote Viability and Proliferation of Mouse Primary Myoblasts

T Padilla‐Benavides, BT Nasipak… - Journal of cellular …, 2015 - Wiley Online Library
Brg1 (Brahma‐related gene 1) is a catalytic component of the evolutionarily conserved
mammalian SWI/SNF ATP‐dependent chromatin remodeling enzymes that disrupt histone …

The chromatin modifying complex CoREST/LSD1 negatively regulates notch pathway during cerebral cortex development

CI Lopez, KE Saud, R Aguilar, FA Berndt… - Developmental …, 2016 - Wiley Online Library
The development of the cerebral cortex is a dynamic and coordinated process in which cell
division, cell death, migration, and differentiation must be highly regulated to acquire the …

ATP‐Dependent Chromatin Remodeling Complex in the Lineage Specification of Mesenchymal Stem Cells

W Du, D Guo, W Du - Stem Cells International, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) present in multiple tissues can self‐renew and differentiate
into multiple lineages including the bone, cartilage, muscle, cardiac tissue, and connective …

Cell cycle gene expression networks discovered using systems biology: significance in carcinogenesis

RE Scott, PN Ghule, JL Stein… - Journal of cellular …, 2015 - Wiley Online Library
The early stages of carcinogenesis are linked to defects in the cell cycle. A series of cell
cycle checkpoints are involved in this process. The G1/S checkpoint that serves to integrate …

From quiescence to repair: C/EBPβ as a regulator of muscle stem cell function in health and disease

H AlSudais, N Wiper‐Bergeron - The FEBS Journal, 2022 - Wiley Online Library
CCAAT/Enhancer Binding protein beta (C/EBPβ) is a transcriptional regulator involved in
numerous physiological processes. Herein, we describe a role for C/EBPβ as a regulator of …

SUMO-specific protease 2 (SENP2) suppresses browning of white adipose tissue through C/EBPβ modulation

JS Lee, S Chae, J Nan, YD Koo, SA Lee, YJ Park… - bioRxiv, 2020 - biorxiv.org
Abstract SUMO-specific protease 2 (SENP2) is highly expressed in white adipose tissue
(WAT) and plays an important role in the early stages of adipogenesis. To investigate the …

[PDF][PDF] SWI/SNF chromatin remodeling complex in regulating mesenchymal stem cell lineage specification

D Chen, X Zhong, K Wang, Y Jiang - J Tissue Sci Eng, 2015 - scholar.archive.org
Abstract Mesenchymal Stem Cells (MSC) can be obtained from various tissues and
differentiate into many different lineages, including osteoblasts, adipocytes, chondrocytes …