[HTML][HTML] Small molecules in targeted cancer therapy: advances, challenges, and future perspectives
L Zhong, Y Li, L Xiong, W Wang, M Wu… - Signal transduction and …, 2021 - nature.com
Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs,
targeted therapeutic drugs have become mainstream cancer treatments. Since the first …
targeted therapeutic drugs have become mainstream cancer treatments. Since the first …
Biosensors: the new wave in cancer diagnosis
B Bohunicky, SA Mousa - Nanotechnology, science and …, 2010 - Taylor & Francis
The earlier cancer can be detected, the better the chance of a cure. Currently, many cancers
are diagnosed only after they have metastasized throughout the body. Effective, accurate …
are diagnosed only after they have metastasized throughout the body. Effective, accurate …
[HTML][HTML] Hepatocellular carcinoma: causes, mechanism of progression and biomarkers
Hepatocellular Carcinoma (HCC) is one of the most common malignant tumours in the
world. It is a heterogeneous group of a tumour that vary in risk factor and genetic and …
world. It is a heterogeneous group of a tumour that vary in risk factor and genetic and …
Models of hepatotoxicity and the underlying cellular, biochemical and immunological mechanism (s): a critical discussion
DK Ingawale, SK Mandlik, SR Naik - Environmental toxicology and …, 2014 - Elsevier
Liver is a primary organ involved in biotransformation of food and drugs. Hepatic diseases
are a major worldwide problem. Hepatic disorders are mainly caused by toxic chemicals …
are a major worldwide problem. Hepatic disorders are mainly caused by toxic chemicals …
β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular …
G Zhang, J He, X Ye, J Zhu, X Hu, M Shen, Y Ma… - Cell death & …, 2019 - nature.com
Hepatocellular carcinoma (HCC), a common liver malignancy worldwide, has high morbidity
and mortality. β-Thujaplicin, a tropolone derivative, has been used in some health-care …
and mortality. β-Thujaplicin, a tropolone derivative, has been used in some health-care …
Organophosphate-induced brain damage: mechanisms, neuropsychiatric and neurological consequences, and potential therapeutic strategies
Y Chen - Neurotoxicology, 2012 - Elsevier
Organophosphate (OP)-induced brain damage is defined as progressive damage to the
brain, resulting from the cholinergic neuronal excitotoxicity and dysfunction induced by OP …
brain, resulting from the cholinergic neuronal excitotoxicity and dysfunction induced by OP …
[HTML][HTML] Mechanisms of resistance to sorafenib and the corresponding strategies in hepatocellular carcinoma
B Zhai, XY Sun - World journal of hepatology, 2013 - ncbi.nlm.nih.gov
Sorafenib, the unique drug as first-line treatment for advanced hepatocellular carcinoma
(HCC), has opened a window of hope after searching for effective agents to combat HCC for …
(HCC), has opened a window of hope after searching for effective agents to combat HCC for …
Metformin incombination with curcumin inhibits the growth, metastasis, and angiogenesis of hepatocellular carcinoma in vitro and in vivo
HH Zhang, Y Zhang, YN Cheng, FL Gong… - Molecular …, 2018 - Wiley Online Library
Hepatocellular carcinoma (HCC) has poor prognosis due to the advanced disease stages
by the time it is diagnosed, high recurrence rates and metastasis. In the present study, we …
by the time it is diagnosed, high recurrence rates and metastasis. In the present study, we …
Potential Anti-Inflammatory Effects of the Hydrophilic Fraction of Pomegranate (Punica granatum L.) Seed Oil on Breast Cancer Cell Lines
S Costantini, F Rusolo, V De Vito, S Moccia… - Molecules, 2014 - mdpi.com
In this work, we characterized conjugated linolenic acids (eg, punicic acid) as the major
components of the hydrophilic fraction (80% aqueous methanol extract) from pomegranate …
components of the hydrophilic fraction (80% aqueous methanol extract) from pomegranate …
1, 8-Cineole promotes G0/G1 cell cycle arrest and oxidative stress-induced senescence in HepG2 cells and sensitizes cells to anti-senescence drugs
Abstract Aims 1, 8-Cineole is a plant-derived monoterpene and a major constituent of
Eucalyptus essential oil. Previously, we demonstrated that 1, 8-cineole inhibited …
Eucalyptus essential oil. Previously, we demonstrated that 1, 8-cineole inhibited …