Calcium phosphate-based biomaterials for bone repair

X Hou, L Zhang, Z Zhou, X Luo, T Wang… - Journal of functional …, 2022 - mdpi.com
Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …

Electrical stimulation in bone tissue engineering treatments

L Leppik, KMC Oliveira, MB Bhavsar… - European Journal of …, 2020 - Springer
Electrical stimulation (EStim) has been shown to promote bone healing and regeneration
both in animal experiments and clinical treatments. Therefore, incorporating EStim into …

Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo

M Levin - Molecular biology of the cell, 2014 - Am Soc Cell Biol
In addition to biochemical gradients and transcriptional networks, cell behavior is regulated
by endogenous bioelectrical cues originating in the activity of ion channels and pumps …

Current views on calcium phosphate osteogenicity and the translation into effective bone regeneration strategies

YC Chai, A Carlier, J Bolander, SJ Roberts, L Geris… - Acta biomaterialia, 2012 - Elsevier
Calcium phosphate (CaP) has traditionally been used for the repair of bone defects because
of its strong resemblance to the inorganic phase of bone matrix. Nowadays, a variety of …

Molecular bioelectricity in developmental biology: new tools and recent discoveries: control of cell behavior and pattern formation by transmembrane potential …

M Levin - Bioessays, 2012 - Wiley Online Library
Significant progress in the molecular investigation of endogenous bioelectric signals during
pattern formation in growing tissues has been enabled by recently developed techniques …

Influence of electrotaxis on cell behaviour

B Cortese, IE Palamà, S D'Amone, G Gigli - Integrative Biology, 2014 - academic.oup.com
Understanding the mechanism of cell migration and interaction with the microenvironment is
not only of critical significance to the function and biology of cells, but also has extreme …

Endogenous electric fields as guiding cue for cell migration

RHW Funk - Frontiers in physiology, 2015 - frontiersin.org
This review covers two topics:(1)“membrane potential of low magnitude and related electric
fields (bioelectricity)” and (2)“cell migration under the guiding cue of electric fields (EF).” …

Regulation of cell behavior and tissue patterning by bioelectrical signals: challenges and opportunities for biomedical engineering

M Levin, CG Stevenson - Annual review of biomedical …, 2012 - annualreviews.org
Achieving control over cell behavior and pattern formation requires molecular-level
understanding of regulatory mechanisms. Alongside transcriptional networks and …

Endogenous voltage gradients as mediators of cell-cell communication: strategies for investigating bioelectrical signals during pattern formation

DS Adams, M Levin - Cell and tissue research, 2013 - Springer
Alongside the well-known chemical modes of cell-cell communication, we find an important
and powerful system of bioelectrical signaling: changes in the resting voltage potential (V …

Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities

M Levin - Wiley Interdisciplinary Reviews: Systems Biology and …, 2013 - Wiley Online Library
Transformative impact in regenerative medicine requires more than the reprogramming of
individual cells: advances in repair strategies for birth defects or injuries, tumor …