Human cartilage biomechanics: experimental and theoretical approaches towards the identification of mechanical properties in healthy and osteoarthritic conditions

E Belluzzi, S Todros, A Pozzuoli, P Ruggieri… - Processes, 2023 - mdpi.com
Articular cartilage is a complex connective tissue with the fundamental functions of load
bearing, shock absorption and lubrication in joints. However, traumatic events, aging and …

Quantitative MRI of articular cartilage and its clinical applications

X Li, S Majumdar - Journal of Magnetic Resonance Imaging, 2013 - Wiley Online Library
Cartilage is one of the most essential tissues for healthy joint function and is compromised in
degenerative and traumatic joint diseases. There have been tremendous advances during …

Bioprinting complex cartilaginous structures with clinically compliant biomaterials

M Kesti, C Eberhardt, G Pagliccia… - Advanced Functional …, 2015 - Wiley Online Library
Bioprinting is an emerging technology for the fabrication of patient‐specific, anatomically
complex tissues and organs. A novel bioink for printing cartilage grafts is developed based …

[HTML][HTML] 3D printed PCL/GelMA biphasic scaffold boosts cartilage regeneration using co-culture of mesenchymal stem cells and chondrocytes: In vivo study

Y Cao, P Cheng, S Sang, C Xiang, Y An, X Wei, Y Yan… - Materials & Design, 2021 - Elsevier
Cartilage injury is difficult to self-repair, which poses a challenge to scaffold design and
selection of seeded cells for cartilage tissue engineering. In this study, we presented a …

Prestructural cartilage assessment using MRI

TM Link, J Neumann, X Li - Journal of Magnetic Resonance …, 2017 - Wiley Online Library
Cartilage loss is irreversible, and to date, no effective pharmacotherapies are available to
protect or regenerate cartilage. Quantitative prestructural/compositional MR imaging …

[HTML][HTML] Contrast enhanced computed tomography can predict the glycosaminoglycan content and biomechanical properties of articular cartilage

PN Bansal, NS Joshi, V Entezari, MW Grinstaff… - Osteoarthritis and …, 2010 - Elsevier
OBJECTIVE: An early hallmark of osteoarthritis (OA) is the progressive loss of
glycosaminoglycans (GAGs), the extracellular matrix (ECM) component of articular cartilage …

Elastic, viscoelastic and fibril-reinforced poroelastic material properties of healthy and osteoarthritic human tibial cartilage

M Ebrahimi, S Ojanen, A Mohammadi… - Annals of Biomedical …, 2019 - Springer
Articular cartilage constituents (collagen, proteoglycans, fluid) are significantly altered during
osteoarthritis (OA). A fibril-reinforced poroelastic (FRPE) material model can separate the …

Quantitative parametric MRI of articular cartilage: a review of progress and open challenges

DA Binks, RJ Hodgson, ME Ries… - The British journal of …, 2013 - academic.oup.com
With increasing life expectancies and the desire to maintain active lifestyles well into old
age, the impact of the debilitating disease osteoarthritis (OA) and its burden on healthcare …

Subject-specific analysis of joint contact mechanics: application to the study of osteoarthritis and surgical planning

CR Henak, AE Anderson… - Journal of …, 2013 - asmedigitalcollection.asme.org
Advances in computational mechanics, constitutive modeling, and techniques for subject-
specific modeling have opened the door to patient-specific simulation of the relationships …

Emerging role of integrated PET-MRI in osteoarthritis

A Jena, S Taneja, P Rana, N Goyal, A Vaish… - Skeletal Radiology, 2021 - Springer
Osteoarthritis (OA) is a common degenerative disorder of the articular cartilage, which is
associated with hypertrophic changes in the bone, synovial inflammation, subchondral …