Recent advances in theoretical calculations of indirect spin–spin coupling constants

LB Krivdin, RH Contreras - Annual Reports on NMR Spectroscopy, 2007 - Elsevier
Recent trends in theoretical calculations of indirect spin–spin coupling constants covering
the period of May 2003–July 2006 are outlined with the emphasis on the currently used …

Zwitterionic glycosidase inhibitors: salacinol and related analogues

S Mohan, BM Pinto - Carbohydrate Research, 2007 - Elsevier
Natural products with interesting biological properties and structural diversity have often
served as valuable lead drug candidates for the treatment of human diseases. Salacinol, a …

Stereoselective C-Glycosylation Reactions of Pyranoses:  The Conformational Preference and Reactions of the Mannosyl Cation

CG Lucero, KA Woerpel - The Journal of Organic Chemistry, 2006 - ACS Publications
A systematic study of C-glycosylations of acetals related to mannose and other pyranoses
was conducted. The C-5 alkoxyalkyl group provides only a modest influence on …

Electrostatic interactions in cations and their importance in biology and chemistry

DM Smith, KA Woerpel - Organic & Biomolecular Chemistry, 2006 - pubs.rsc.org
Electrostatic effects exert strongly stabilizing influences on cations, in many cases controlling
the conformational preferences of these cations. The lowest energy conformers are ones …

Biological evaluation of de-O-sulfonated analogs of salacinol, the role of sulfate anion in the side chain on the α-glucosidase inhibitory activity

G Tanabe, K Yoshikai, T Hatanaka… - Bioorganic & medicinal …, 2007 - Elsevier
De-O-sulfonated analogs (10a, Y−= CH3OSO3 and 10b, Y−= Cl) of salacinol, a naturally
occurring glycosidase inhibitor, and its diastereomer (12a, Y−= CH3OSO3) with l-thiosugar …

Reconciling solvent effects on rotamer populations in carbohydrates A joint MD and NMR analysis

J Gonzalez-Outeiriño, KN Kirschner… - Canadian journal of …, 2006 - cdnsciencepub.com
Il est bien connu que les préférences rotationnelles des groupes hydroxyméthyles des
pyranosides dépend de l'environnement local que ce soit à l'état solide, en solution ou en …

Rational Design and Expedient Synthesis of Heparan Sulfate Mimetics from Natural Aminoglycosides for Structure and Activity Relationship Studies

J Wakpal, V Pathiranage, AR Walker… - Angewandte …, 2023 - Wiley Online Library
Heparan sulfate (HS) contains variably repeating disaccharide units organized into high‐
and low‐sulfated domains. This rich structural diversity enables HS to interact with many …

Indolizidine and quinolizidine alkaloids

JP Michael - Natural product reports, 2005 - pubs.rsc.org
Covering: July 2003 to June 2004. Previous review: Nat. Prod. Rep., 2004, 21, 625. This
review covers the isolation, structure determination, synthesis, chemical transformations and …

New chain-extended analogues of salacinol and blintol and their glycosidase inhibitory activities. Mapping the active-site requirements of human maltase …

R Nasi, L Sim, DR Rose, BM Pinto - The Journal of organic …, 2007 - ACS Publications
The synthesis of new chain-extended sulfonium and selenonium salts of 1, 4-anhydro-4-thio-
(or 4-seleno)-d-arabinitol, analogues of the naturally occurring glycosidase inhibitor …

Combined Chemical, Biological and Theoretical DFT‐QTAIM Study of Potent Glycosidase Inhibitors Based on Quaternary Indolizinium Salts

P Šafář, J Žúžiová, Š Marchalín… - European Journal of …, 2012 - Wiley Online Library
Six novel enantiopure epimeric indolizidinediols have been easily prepared in high yields
by an effective and well‐established regioselective THF ring‐opening reaction as a key step …