Molecular mechanisms of oxidative stress in asthma

C Michaeloudes, H Abubakar-Waziri, R Lakhdar… - Molecular aspects of …, 2022 - Elsevier
The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

Air pollution and its effects on the immune system

DA Glencross, TR Ho, N Camina… - Free Radical Biology …, 2020 - Elsevier
A well-functioning immune system is vital for a healthy body. Inadequate and excessive
immune responses underlie diverse pathologies such as serious infections, metastatic …

Immunologic mechanisms in asthma

T Boonpiyathad, ZC Sözener, P Satitsuksanoa… - Seminars in …, 2019 - Elsevier
Asthma is a chronic airway disease, which affects more than 300 million people. The
pathogenesis of asthma exhibits marked heterogeneity with many phenotypes defining …

Environmental exposures and mechanisms in allergy and asthma development

LB Murrison, EB Brandt, JB Myers… - The Journal of clinical …, 2019 - Am Soc Clin Investig
Environmental exposures interplay with human host factors to promote the development and
progression of allergic diseases. The worldwide prevalence of allergic disease is rising as a …

The immunology of asthma

BN Lambrecht, H Hammad - Nature immunology, 2015 - nature.com
Asthma is a common disease that affects 300 million people worldwide. Given the large
number of eosinophils in the airways of people with mild asthma, and verified by data from …

Outdoor air pollution and asthma

M Guarnieri, JR Balmes - The Lancet, 2014 - thelancet.com
Traffic and power generation are the main sources of urban air pollution. The idea that
outdoor air pollution can cause exacerbations of pre-existing asthma is supported by an …

Potential role of polycyclic aromatic hydrocarbons in air pollution-induced non-malignant respiratory diseases

M Låg, J Øvrevik, M Refsnes, JA Holme - Respiratory research, 2020 - Springer
Epidemiological studies have found strong associations between air pollution and
respiratory effects including development and/or exacerbation of asthma and chronic …

Aeroparticles, composition, and lung diseases

CI Falcon-Rodriguez, AR Osornio-Vargas… - Frontiers in …, 2016 - frontiersin.org
Urban air pollution is a serious worldwide problem due to its impact on human health. In the
past 60 years, growing evidence established a correlation between exposure to air …

Detrimental effects of microplastic exposure on normal and asthmatic pulmonary physiology

K Lu, KP Lai, T Stoeger, S Ji, Z Lin, X Lin… - Journal of hazardous …, 2021 - Elsevier
Concerns that airborne microplastics (MP) may be detrimental to human health are rising.
However, research on the effects of MP on the respiratory system are limited. We tested the …

IL-17 in severe asthma. Where do we stand?

J Chesné, F Braza, G Mahay, S Brouard… - American journal of …, 2014 - atsjournals.org
Asthma is a major chronic disease ranging from mild to severe refractory disease and is
classified into various clinical phenotypes. Severe asthma is difficult to treat and frequently …