CYP3A is an enzyme subfamily in the cytochrome P450 (CYP) superfamily and includes
isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are indiscriminate …

Background: Available in-vitro and animal studies indicate that inflammation impacts
cytochromes P450 (CYP) activity via multiple and complex transcriptional and post …

Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) infection, is a severe acute respiratory syndrome with an …

Decades of research into the molecular mechanisms of cancer and the development of
novel therapeutics have yielded a number of remarkable successes. However, our ability to …

Immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriatic arthritis,
peripheral and/or axial spondyloarthritis, Crohn's disease, and ulcerative colitis, are …

Diabetes mellitus is a metabolic disease that causes a hyperglycemic status which leads,
over time, to serious damage to the heart, blood vessels, eyes, kidneys and nerves. The …

Mathematical models, such as physiologically‐based pharmacokinetic models, are used to
predict, for example, drug disposition and toxicity. However, populations differ in the …

Lately, matcha green tea has gained popularity as a beverage and food additive. It has
proved to be effective in preventing obesity and related metabolic syndromes. However, the …

When skeletal muscle is damaged, satellite cells (SCs) are activated to proliferate rapidly
and fuse with the damaged muscle fibers to form new muscle fibers, thereby promoting …

Given the increase in bacterial resistance and the decrease in the development of new
antibiotics, the appropriate use of old antimicrobials has become even more compulsory …