An overview of influenza viruses and vaccines

RF Nuwarda, AA Alharbi, V Kayser - Vaccines, 2021 - mdpi.com
Influenza remains one of the major public health concerns because it causes annual
epidemics and can potentially instigate a global pandemic. Numerous countermeasures …

Traditional and new influenza vaccines

SS Wong, RJ Webby - Clinical microbiology reviews, 2013 - Am Soc Microbiol
The challenges in successful vaccination against influenza using conventional approaches
lie in their variable efficacy in different age populations, the antigenic variability of the …

Theoretical basis of the test-negative study design for assessment of influenza vaccine effectiveness

SG Sullivan, EJ Tchetgen Tchetgen… - American journal of …, 2016 - academic.oup.com
Influenza viruses undergo frequent antigenic changes. As a result, the viruses circulating
change within and between seasons, and the composition of the influenza vaccine is …

Antibody landscapes after influenza virus infection or vaccination

JM Fonville, SH Wilks, SL James, A Fox, M Ventresca… - Science, 2014 - science.org
We introduce the antibody landscape, a method for the quantitative analysis of antibody-
mediated immunity to antigenically variable pathogens, achieved by accounting for …

[图书][B] Manual for the laboratory diagnosis and virological surveillance of influenza

World Health Organization - 2011 - apps.who.int
Manual for the laboratory diagnosis and virological surveillance of influenza Page 1 WHO Global
Influenza Surveillance Network Manual for the laboratory diagnosis and virological surveillance …

H3N2 influenza viruses in humans: Viral mechanisms, evolution, and evaluation

JD Allen, TM Ross - Human vaccines & immunotherapeutics, 2018 - Taylor & Francis
Annual seasonal influenza vaccines are composed of two influenza A strains representing
the H1N1 and H3N2 subtypes, and two influenza B strains representing the Victoria and …

Terminally modified RNA

T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49447811&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Integrating influenza antigenic dynamics with molecular evolution

T Bedford, MA Suchard, P Lemey, G Dudas, V Gregory… - elife, 2014 - elifesciences.org
Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade
host immunity acquired to previous virus strains. Antigenic phenotype is often assessed …

Influenza seasonality in the tropics and subtropics–when to vaccinate?

S Hirve, LP Newman, J Paget, E Azziz-Baumgartner… - PloS one, 2016 - journals.plos.org
Background The timing of the biannual WHO influenza vaccine composition selection and
production cycle has been historically directed to the influenza seasonality patterns in the …

Evolution of the receptor binding properties of the influenza A (H3N2) hemagglutinin

YP Lin, X Xiong, SA Wharton… - Proceedings of the …, 2012 - National Acad Sciences
The hemagglutinin (HA) of influenza A (H3N2) virus responsible for the 1968 influenza
pandemic derived from an avian virus. On introduction into humans, its receptor binding …