Abstract 3D bioprinting is a pioneering technology that enables fabrication of biomimetic,
multiscale, multi-cellular tissues with highly complex tissue microenvironment, intricate …

Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

Just as in clay moulding or glass blowing, physically sculpting biological structures requires
the constituent material to locally flow like a fluid while maintaining overall mechanical …

Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

Tissue morphogenesis requires the collective, coordinated motion and deformation of a
large number of cells. Vertex model simulations for tissue mechanics have been developed …

We review the general hydrodynamic theory of active soft materials that is motivated in
particular by biological matter. We present basic concepts of irreversible thermodynamics of …

The goal of tissue engineering is to mitigate the critical shortage of donor organs via in vitro
fabrication of functional biological structures. Tissue engineering is one of the most …

The mechanical properties of the cellular microenvironment and their spatiotemporal
variations are thought to play a central role in sculpting embryonic tissues, maintaining …

In this paper we present an overview of agent-based models that are used to simulate
mechanical and physiological phenomena in cells and tissues, and we discuss underlying …

Biofabrication of living structures with desired topology and functionality requires the
interdisciplinary effort of practitioners of the physical, life and engineering sciences. Such …