Primary hypothyroidism and Alzheimer's Disease: a tale of two

FH AlAnazi, HM Al-Kuraishy, A Alexiou… - Cellular and Molecular …, 2023 - Springer
Hypothyroidism (HPT) HPT could be a risk factor for the development and progression of
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …

[HTML][HTML] The role of thyroid dysfunction in Alzheimer's disease: a systematic review and meta-analysis

A Salehipour, M Dolatshahi, M Haghshomar - The journal of prevention of …, 2023 - Elsevier
Imbalances in thyroid hormones have been linked with Alzheimer's dementia. Several
studies have reported an association between thyroid disorders, such as hyper-or …

[HTML][HTML] Cadmium-promoted thyroid hormones disruption mediates ROS, inflammation, Aβ and Tau proteins production, gliosis, spongiosis and neurodegeneration in …

E Sola, P Moyano, A Flores, JM García, J García… - Chemico-Biological …, 2023 - Elsevier
Cadmium (Cd) produces cognition decline following single and repeated treatment,
although the complete mechanisms are still unrevealed. Basal forebrain (BF) cholinergic …

[HTML][HTML] Melissa officinalis extract suppresses endoplasmic reticulum stress-induced apoptosis in the brain of hypothyroidism-induced rats exposed to γ-radiation

OAR Abo-Zaid, FSM Moawed, EFS Taha… - Cell Stress and …, 2023 - Elsevier
The purpose of this study was to demonstrate the neuroprotective effect of Melissa officinalis
extract (MEE) against brain damage associated with hypothyroidism induced by …

Phycocyanobilin is the molecule responsible for the nephroprotective action of phycocyanin in acute kidney injury caused by mercury

E Garcia-Pliego, M Franco-Colin, P Rojas-Franco… - Food & Function, 2021 - pubs.rsc.org
C-Phycocyanin (CPC) exerts therapeutic, antioxidant, anti-inflammatory and
immunomodulatory actions. It prevents oxidative stress and acute kidney damage caused by …

Association between thyroid function and Alzheimer's disease: A systematic review

PBS Figueroa, AFF Ferreira, LR Britto… - Metabolic Brain …, 2021 - Springer
Alterations in metabolic parameters have been associated with an increased risk of
dementia, among which thyroid function has gained great importance in Alzheimer's disease …

Thyroxine restores hippocampal neurogenesis and synaptogenesis in a male rat model of carbimazole-induced hypothyroidism: a histological study

EA Farag, SA Filobbos, NM Afifi, ST Mahmoud… - Beni-Suef University …, 2023 - Springer
Background Adult-onset hypothyroidism has a deleterious effect on hippocampal cognitive
and memory functions. This study was performed to evaluate the possible therapeutic effect …

Gallic acid prevents the oxidative and endoplasmic reticulum stresses in the hippocampus of adult-onset hypothyroid rats

V Blas-Valdivia, M Franco-Colín… - Frontiers in …, 2021 - frontiersin.org
Thyroid hormone is essential for hippocampal redox environment and neuronal viability in
adulthood, where its deficiency causes hypothyroidism related to oxidative and endoplasmic …

Recent insights into the effect of endoplasmic reticulum stress in the pathophysiology of intestinal Ischaemia‒reperfusion injury

J Zhang, X Zhang, Y Liu, Y Shi, F Chen… - … and Biophysical Research …, 2024 - Elsevier
Intestinal ischaemia‒reperfusion (I/R) injury is a surgical emergency. This condition is
associated with a high mortality rate. At present, there are limited number of efficient …

[HTML][HTML] Aerobic Exercise Mediated Increase in BDNF Expression Ameliorates Depression in Propylthiouracil-Induced Hypothyroidism in Adult Rats.

W Ezzat, MS Abd-El Hamid - Journal of Affective Disorders Reports, 2021 - Elsevier
Background: The prevalence of depression with hypothyroidism is high. Objective: To study
the ability of aerobic exercise to improve hypothyroidism associated depression and to …