Inhibitors of DNA binding and cell differentiation (Id) proteins are members of the large
family of the helix-loop-helix (HLH) transcription factors, but they lack any DNA-binding motif …

Highly conserved Inhibitors of DNA-Binding (ID1–ID4) genes encode multi-functional
proteins whose transcriptional activity is based on dominant negative inhibition of basic helix …

Exosomes released by tumor cells have been recently identified as important determinants
of tumor progression. They often carry circular RNAs that are differentially expressed in …

Here, I propose that cancer stem cells (CSCs) would be equivalent to para-embryonic stem
cells (p-ESCs), derived from adult cells de-re-programmed to a ground state. p-ESCs would …

Quiescence is essential for the long-term maintenance of adult stem cells but how stem cells
maintain quiescence is poorly understood. Here, we show that neural stem cells (NSCs) in …

Glioma is recognized as a highly angiogenic malignant brain tumor. Vasculogenic mimicry
(VM) greatly restricts the therapeutic effect of anti-angiogenic tumor therapy for glioma …

Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain
tumor in humans, whose invasiveness and proliferation are associated with poor prognosis …

Background Metastasis remains the biggest obstacle for breast cancer treatment. Therefore,
identification of specific biomarker of metastasis is very necessary. The RNA binding protein …

Glioblastoma (GBM) is the most aggressive cancer of the brain and has a high mortality rate
due to the lack of effective treatment strategy. Clarification of molecular mechanisms of …

Vasculogenic mimicry (VM) is closely related to cancer progression and metastasis,
contributing to poor prognosis in patients with cancer. Resveratrol (RES) is well known to …