The search for the chemistry of life's origin

A Eschenmoser - Tetrahedron, 2007 - Elsevier
The supreme property of chemical matter is its potency to have given rise to the emergence
of life. Yet life's origin continues to be one of the big unanswered questions of natural …

Coenzymes and their role in the evolution of life

A Kirschning - Angewandte Chemie International Edition, 2021 - Wiley Online Library
The evolution of coenzymes, or their impact on the origin of life, is fundamental for
understanding our own existence. Having established reasonable hypotheses about the …

[图书][B] Soils of the past: an introduction to paleopedology

GJ Retallack - 2008 - books.google.com
It has been 10 years since publication of the first edition ofSoils of the Past. In that time the
subject of paleopedology hasgrown rapidly, and established itself within the mainstream …

Remnants of an ancient metabolism without phosphate

JE Goldford, H Hartman, TF Smith, D Segrè - Cell, 2017 - cell.com
Phosphate is essential for all living systems, serving as a building block of genetic and
metabolic machinery. However, it is unclear how phosphate could have assumed these …

Thioesters provide a plausible prebiotic path to proto-peptides

M Frenkel-Pinter, M Bouza, FM Fernández… - Nature …, 2022 - nature.com
It is widely assumed that the condensation of building blocks into oligomers and polymers
was important in the origins of life. High activation energies, unfavorable thermodynamics …

Elongation of oligopeptides in a simulated submarine hydrothermal system

E Imai, H Honda, K Hatori, A Brack, K Matsuno - Science, 1999 - science.org
Oligomerization of a peptide was attempted in a flow reactor that simulated a submarine
hydrothermal system. When fluid containing glycine repeatedly circulated through the hot …

Ribozyme catalysis of metabolism in the RNA world

X Chen, N Li, AD Ellington - Chemistry & biodiversity, 2007 - Wiley Online Library
In vitro selection has proven to be a useful means of explore the molecules and catalysts
that may have existed in a primoridal 'RNA world'. By selecting binding species (aptamers) …

On the aqueous origins of the condensation polymers of life

D Whitaker, MW Powner - Nature Reviews Chemistry, 2024 - nature.com
Water is essential for life as we know it, but it has paradoxically been considered inimical to
the emergence of life. Proteins and nucleic acids have sustained evolution and life for …

Prebiotic synthesis of phosphoenol pyruvate by α-phosphorylation-controlled triose glycolysis

AJ Coggins, MW Powner - Nature Chemistry, 2017 - nature.com
Phosphoenol pyruvate is the highest-energy phosphate found in living organisms and is one
of the most versatile molecules in metabolism. Consequently, it is an essential intermediate …

Plants need their vitamins too

AG Smith, MT Croft, M Moulin, ME Webb - Current opinion in plant biology, 2007 - Elsevier
Over recent years, the pathways for the biosynthesis of many vitamins have been elucidated
at the molecular level in plants, and several unique features are emerging. One is that the …