Interactions of IDO and the kynurenine pathway with cell transduction Systems and metabolism at the inflammation–cancer interface
TW Stone, RO Williams - Cancers, 2023 - mdpi.com
Simple Summary There is clear evidence that inflammation can contribute to the
development of cancers, but the underlying mechanisms are not fully understood. This …
development of cancers, but the underlying mechanisms are not fully understood. This …
FoxO transcription factors: Applicability as a novel immune cell regulators and therapeutic targets in oxidative stress-related diseases
ME Kim, DH Kim, JS Lee - International Journal of Molecular Sciences, 2022 - mdpi.com
Forkhead box O transcription factors (FoxOs) play an important role in maintaining normal
cell physiology by regulating survival, apoptosis, autophagy, oxidative stress, the …
cell physiology by regulating survival, apoptosis, autophagy, oxidative stress, the …
FOXO1 orchestrates the intestinal homeostasis via neuronal signaling in group 3 innate lymphoid cells
F Shao, Z Liu, Q Wei, D Yu, M Zhao, X Zhang… - Journal of Experimental …, 2023 - rupress.org
The neuro-immune regulation is associated with homeostasis of the intestine. Intestinal
group 3 innate lymphoid cells (ILC3s) are tissue-resident lymphocytes whose functions are …
group 3 innate lymphoid cells (ILC3s) are tissue-resident lymphocytes whose functions are …
Cross-species regulatory network analysis identifies FOXO1 as a driver of ovarian follicular recruitment
AE Kramer, A Berral-González, KM Ellwood, S Ding… - Scientific Reports, 2024 - nature.com
The transcriptional regulation of gene expression in the latter stages of follicular
development in laying hen ovarian follicles is not well understood. Although differentially …
development in laying hen ovarian follicles is not well understood. Although differentially …
Deletion of the foxO1 gene reduces hypoxia tolerance in zebrafish embryos by influencing erythropoiesis
LL Shi, K Ye, SZ Wang, CJ Hou, AK Song, H Liu… - Life Sciences, 2024 - Elsevier
Abstract FoxO1 (Forkhead box O1) belongs to the evolutionarily conserved FoxO subfamily
and is involved in diverse physiologic processes, including apoptosis, cell cycle, DNA …
and is involved in diverse physiologic processes, including apoptosis, cell cycle, DNA …
Machine Learning Uncovers Vascular Endothelial Cell Identity Genes by Expression Regulation Features in Single Cells
KS Arulsamy, B Xia, H Chen, L Zhang, K Chen - BioRxiv, 2024 - biorxiv.org
Deciphering cell identity genes is pivotal to understanding cell differentiation, development,
and many diseases involving cell identity dysregulation. Here, we introduce SCIG, a …
and many diseases involving cell identity dysregulation. Here, we introduce SCIG, a …
T-BET and EOMES: the powerful pair in human NK cell differentiation and ILC3 plasticity
L Kiekens - 2022 - biblio.ugent.be
The innate immune system is one of the body's own defense mechanisms to battle invading
pathogens and the emergence and outgrowth of malignant cells. They are the first to …
pathogens and the emergence and outgrowth of malignant cells. They are the first to …