Inflammasomes are cytoplasmic multiprotein complexes that coordinate inflammatory
responses, including those that take place during pregnancy. Inflammasomes and their …

Major clinical challenges for obstetricians and neonatologists result from early cervix
remodeling and preterm birth. Complications related to cervix remodeling or delivery …

We start by describing the functions of the uterus, its structure, both gross and fine,
innervation and blood supply. It is interesting to note the diversity of the female's …

Problem Inflammasomes are signaling platforms that, upon sensing pathogens and sterile
stressors, mediate the release of mature forms of interleukin (IL)‐1β and IL‐18. The aims of …

The female reproductive tract undergoes remarkable functional and structural changes
associated with cycling, conception and pregnancy, and it is likely advantageous to both …

Pregnancy and childbirth are among the most dramatic physiological and emotional
transformations of a lifetime. Despite their central importance to human survival, many gaps …

OBJECTIVE: Clinically, vaginal progesterone (VP) and 17 alpha-hydroxyprogesterone
caproate (17P) have been shown to prevent preterm birth (PTB) in high-risk populations. We …

Background Improvement of bladder emptying by modulating afferent nerve activity is an
attractive therapeutic strategy for detrusor underactivity. Transient receptor potential vanilloid …

Abstract Objective: Human β-defensin-3 (HBD-3) has a broad spectrum of antimicrobial
activity, and activity and, therefore, plays a central role in host defense mechanisms against …

Remodeling of the cervix is a critical early component of parturition and resembles an
inflammatory process. Infiltration and activation of myeloid immune cells along with …