A wealth of biochemical and cellular data, accumulated over several years by multiple
groups, has provided a great degree of insight into the molecular mechanisms of actions of …

The SAGA complex is an evolutionarily conserved transcriptional coactivator that regulates
gene expression through its histone acetyltransferase and deubiquitylase activities …

Abstract Backgrounds/Aims: Long non-coding RNA (lncRNA) X-inactive specific transcript
(XIST) is involved in the progression of several tumors. The interaction between lncRNA and …

Background Gastric cancer (GC) ranks the fifth most common cancer, and chemotherapy is
one of the most common treatments for GC. However, chemoresistance limits the …

CCL14 is a member of CC chemokines and its role in hepatocellular carcinoma (HCC) is still
unknown. In this study, CCL14 expression were analyzed by tissue microarray (TMA) …

Solid tumors are 3D assemblies of cancer cells, together with multiple stromal cell types
within an extracellular matrix. Yet, the vast majority of cell-based studies to characterize …

Cervical cancer (CC) is a deadly gynecological tumor worldwide. Otubain 2 (OTUB2) has
been recently identified as an oncogene in human malignancies. However, its expression …

Hyperplasia of mammary glands (HMG) is considered a precancerous condition with a risk
of malignant transformation, highlighting the necessity of proactive treatment in the early …

ABSTRACT The ADA3 (Alteration/Deficiency in Activation 3) protein is an essential adaptor
component of several L ysine A cetyl t ransferase (KAT) complexes involved in chromatin …

Gastric cancer (GC) is a leading global cause of cancer-related mortality, necessitating
urgent research on its pathogenesis, prevention, and treatment. In this study, we …