Paracrine mechanisms of mesenchymal stromal cells in angiogenesis

S Maacha, H Sidahmed, S Jacob… - Stem cells …, 2020 - Wiley Online Library
The role of the mesenchymal stromal cell‐(MSC‐) derived secretome is becoming
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …

Activation, homing, and role of the mesenchymal stem cells in the inflammatory environment

L Zachar, D Bačenková, J Rosocha - Journal of inflammation …, 2016 - Taylor & Francis
Human mesenchymal stem cells (MSCs) are considered to be a promising source of cells in
regenerative medicine. They have large potential to differentiate into various tissue-specific …

Human bone marrow-and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species

SR Baglio, K Rooijers, D Koppers-Lalic… - Stem cell research & …, 2015 - Springer
Introduction Administration of mesenchymal stem cells (MSCs) represents a promising
treatment option for patients suffering from immunological and degenerative disorders …

Genetic stability of mesenchymal stromal cells for regenerative medicine applications: a fundamental biosafety aspect

S Neri - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem/stromal cells (MSC) show widespread application for a variety of clinical
conditions; therefore, their use necessitates continuous monitoring of their safety. The risk …

Cryopreserved or fresh mesenchymal stromal cells: only a matter of taste or key to unleash the full clinical potential of MSC therapy?

G Moll, S Geißler, R Catar, L Ignatowicz… - … and cryopreservation of …, 2016 - Springer
Mesenchymal stromal cells (MSCs) harbor great therapeutic potential for numerous
diseases. From early clinical trials, success and failure analysis, bench-to-bedside and back …

Long-term cultured mesenchymal stem cells frequently develop genomic mutations but do not undergo malignant transformation

Y Wang, Z Zhang, Y Chi, Q Zhang, F Xu, Z Yang… - Cell Death & …, 2013 - nature.com
Cultured human umbilical cord mesenchymal stem cells (hUC-MSCs) are being tested in
several clinical trials and encouraging outcomes have been observed. To determine …

Use of adipose‐derived mesenchymal stem cells in keratoconjunctivitis sicca in a canine model

AJ Villatoro, V Fernández, S Claros… - BioMed research …, 2015 - Wiley Online Library
Keratoconjunctivitis sicca (KCS) or dry eye disease (DED) is an immune‐mediated
multifactorial disease, with high level of prevalence in humans and dogs. Our aim in this …

[HTML][HTML] Enhanced ex vivo expansion of adult mesenchymal stem cells by fetal mesenchymal stem cell ECM

CP Ng, ARM Sharif, DE Heath, JW Chow, CBY Zhang… - Biomaterials, 2014 - Elsevier
Large-scale expansion of highly functional adult human mesenchymal stem cells (aMSCs)
remains technologically challenging as aMSCs lose self renewal capacity and multipotency …

Native and solubilized decellularized extracellular matrix: a critical assessment of their potential for improving the expansion of mesenchymal stem cells

A Shakouri-Motlagh, AJ O'Connor, SP Brennecke… - Acta Biomaterialia, 2017 - Elsevier
Capturing the promise of mesenchymal stem cell (MSC)-based treatments is currently
limited by inefficient production of cells needed for clinical therapies. During conventional ex …

[HTML][HTML] Mesenchymal stromal cells from pooled mononuclear cells of multiple bone marrow donors as rescue therapy in pediatric severe steroid-refractory graft …

Z Kuçi, H Bönig, H Kreyenberg, M Bunos, A Jauch… - …, 2016 - ncbi.nlm.nih.gov
To circumvent donor-to-donor heterogeneity which may lead to inconsistent results after
treatment of acute graft-versus-host disease with mesenchymal stromal cells generated from …