The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

Cerebral palsy is the most frequent cause of severe physical disability in childhood.
Dyskinetic cerebral palsy (DCP) is the second most common type of cerebral palsy after …

Aim To systematically review evidence for pharmacological/neurosurgical interventions for
managing dystonia in individuals with cerebral palsy (CP) to inform a care pathway. Method …

Aim We performed a meta‐analysis with individual participant data of deep brain stimulation
(DBS) for dystonia in children and young people. Method Three databases (PubMed …

Background Patients with dyskinetic cerebral palsy are often severely impaired with limited
treatment options. The effects of deep brain stimulation (DBS) are less pronounced than …

Background Cerebral palsy (CP) is a disorder of motor function often accompanied by
cognitive impairment. There is a paucity of research focused on cognition in dyskinetic CP …

Abstract Background Lesch–Nyhan syndrome (LNS) is a rare genetic disorder characterized
by a deficiency of hypoxanthine-guanine phosphoribosyltransferase enzyme. It manifests …

Dystonia in childhood may be severely disabling and often unremitting and unrecognized.
Considered a rare disorder, dystonic symptoms in childhood are pervasive in many …

Improved care for people with dystonia presents a number of challenges. Major gaps in
knowledge exist with regard to how to optimize the diagnostic process, how to leverage …

Introduction: Dystonia, one of the most common childhood movement disorders, is often
medically refractory and can lead to profound impacts on the child and their caretakers' …