Nitro-mannich reaction

A Noble, JC Anderson - Chemical Reviews, 2013 - ACS Publications
Reactions that utilize addition of active C− H nucleophiles to C X bonds represent some of
the most fundamental carbon− carbon bond-forming processes in organic chemistry. Of …

Advances in rosin-based chemicals: the latest recipes, applications and future trends

S Kugler, P Ossowicz, K Malarczyk-Matusiak… - Molecules, 2019 - mdpi.com
A comprehensive review of the publications about rosin-based chemicals has been
compiled. Rosin, or colophony, is a natural, abundant, cheap and non-toxic raw material …

A unique approach to the concise synthesis of highly optically active spirooxazolines and the discovery of a more potent oxindole-type phytoalexin analogue

X Jiang, Y Cao, Y Wang, L Liu, F Shen… - Journal of the American …, 2010 - ACS Publications
Drug-lead synthesis through rapid construction of chiral molecular complexity around the
biologically relevant framework using a highly efficient strategy is a key goal of organic …

Heterobimetallic Transition Metal/Rare Earth Metal Bifunctional Catalysis: A Cu/Sm/Schiff Base Complex for Syn-Selective Catalytic Asymmetric Nitro-Mannich …

S Handa, V Gnanadesikan, S Matsunaga… - Journal of the …, 2010 - ACS Publications
The full details of a catalytic asymmetric syn-selective nitro-Mannich reaction promoted by
heterobimetallic Cu/Sm/dinucleating Schiff base complexes are described, demonstrating …

Chiral thioureas—preparation and significance in asymmetric synthesis and medicinal chemistry

F Steppeler, D Iwan, E Wojaczyńska, J Wojaczyński - Molecules, 2020 - mdpi.com
For almost 20 years, thioureas have been experiencing a renaissance of interest with the
emerged development of asymmetric organocatalysts. Due to their relatively high acidity and …

Bifunctional cinchona alkaloid thiourea catalyzed highly efficient, enantioselective aza‐henry reaction of cyclic trifluoromethyl ketimines: synthesis of anti‐HIV drug …

H Xie, Y Zhang, S Zhang, X Chen, W Wang - … Chemie International Edition, 2011 - infona.pl
Highly efficient: The title reaction provides biologically interesting chiral trifluoromethyl
dihydroquinazolinone frameworks in high yields (up to 97%) and with high …

A new family of cinchona-derived bifunctional asymmetric phase-transfer catalysts: Application to the enantio-and diastereoselective nitro-Mannich reaction of …

KM Johnson, MS Rattley, F Sladojevich… - Organic …, 2012 - ACS Publications
A new family of bifunctional H-bond donor phase-transfer catalysts derived from cinchona
alkaloids has been developed and evaluated in the enantio-and diastereoselective nitro …

Expeditious Assembly of a 2‐Amino‐4H‐chromene Skeleton by Using an Enantioselective Mannich Intramolecular Ring Cyclization–Tautomerization Cascade …

Q Ren, WY Siau, Z Du, K Zhang, J Wang - Chemistry–A European Journal, 2011 - infona.pl
Easy to assemble! An enantioselective cascade Mannich intramolecular ring cyclization–
tautomerization reaction of malononitrile with 2‐hydroxyl N‐protected α‐amido sulfone is …

Thiourea-phosphonium salts from amino acids: cooperative phase-transfer catalysts in the enantioselective aza-Henry reaction

D Cao, Z Chai, J Zhang, Z Ye, H Xiao… - Chemical …, 2013 - pubs.rsc.org
Thiourea-phosphonium salts from amino acids : cooperative phase-transfer catalysts in the
enantioselective aza-Henry reaction - Chemical Communications (RSC Publishing) DOI:10.1039/C3CC42864H …

Core scaffold‐inspired concise synthesis of chiral spirooxindole‐pyranopyrimidines with broad‐spectrum anticancer potency

X Jiang, Y Sun, J Yao, Y Cao, M Kai… - Advanced Synthesis …, 2012 - Wiley Online Library
Due to the lack of tumor‐specific anticancer agents, the discovery and development of new
types of highly selective anticancer agents is still a very urgent topic. Herein, we present our …