The synaptonemal complex (SC) is a meiosis-specific scaffold that links homologous
chromosomes from end to end during meiotic prophase and is required for the formation of …

Cohesin is an evolutionary conserved multi‐protein complex that plays a pivotal role in
chromosome dynamics. It plays a role both in sister chromatid cohesion and in establishing …

The proteinaceous zipper-like structure known as the synaptonemal complex (SC), which
forms between pairs of homologous chromosomes during meiosis from yeast to humans …

Although assembly of acentrosomal meiotic spindles has been extensively studied, little is
known about the segregation of chromosomes on these spindles. Here, we show in …

Faithful transmission of the genome through sexual reproduction requires reduction of
genome copy number during meiosis to produce haploid sperm and eggs. Meiosis entails …

Bisphenol A (BPA) is a highly prevalent constituent of plastics that has been associated with
diabetes, cardiovascular disease, and an increased risk of miscarriages in humans. In mice …

Exposure to endocrine disrupting compounds (EDCs), such as bisphenol A (BPA), may
cause adverse health effects in wildlife and humans, but controversy remains as to what …

Proteins of the HORMA domain family play central, but poorly understood, roles in
chromosome organization and dynamics during meiosis. In Caenorhabditis elegans, four …

Sexual reproduction requires the production of haploid gametes (sperm and egg) with only
one copy of each chromosome; fertilization then restores the diploid chromosome content in …

Error-free chromosome segregation is essential for the maintenance of genomic integrity
during cell division. Aurora B, the enzymatic subunit of the Chromosomal Passenger …