The striosome and matrix compartments of the striatum: a path through the labyrinth from neurochemistry toward function

KR Brimblecombe, SJ Cragg - ACS chemical neuroscience, 2017 - ACS Publications
The striatum is a heterogeneous structure with a diverse range of neuron types and
neuromodulators. Three decades of anatomical and biochemical studies have established …

Cholinergic interneurons in the dorsal and ventral striatum: anatomical and functional considerations in normal and diseased conditions

KK Gonzales, Y Smith - Annals of the New York Academy of …, 2015 - Wiley Online Library
Striatal cholinergic interneurons (ChIs) are central for the processing and reinforcement of
reward‐related behaviors that are negatively affected in states of altered dopamine …

Cholinergic circuits in cognitive flexibility

VF Prado, H Janickova, MA Al-Onaizi, MAM Prado - Neuroscience, 2017 - Elsevier
Cognitive flexibility, the ability to adjust behavior in response to new and unexpected
conditions in the environment, is essential for adaptation to new challenges and survival …

Striosome–dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons

JR Crittenden, PW Tillberg, MH Riad… - Proceedings of the …, 2016 - National Acad Sciences
The dopamine systems of the brain powerfully influence movement and motivation. We
demonstrate that striatonigral fibers originating in striosomes form highly unusual bouquet …

The dopamine neuron synaptic map in the striatum

N Chuhma, SJ Oh, S Rayport - Cell reports, 2023 - cell.com
Dopamine neurons project to the striatum to control movement, cognition, and motivation via
slower volume transmission as well as faster dopamine, glutamate, and GABA synaptic …

[HTML][HTML] Impact of perinatal hypoxia on the developing brain

M Piešová, M Mojmír - Physiological research, 2020 - ncbi.nlm.nih.gov
Perinatal hypoxia is still one of the greatest threats to the newborn child, even in developed
countries. However, there is a lack of works which summarize up-to-date information about …

Compartmental function and modulation of the striatum

EM Prager, JL Plotkin - Journal of neuroscience research, 2019 - Wiley Online Library
The striatum plays a central role in guiding numerous complex behaviors, ranging from
motor control to action selection and reward learning. The diverse responsibilities of the …

[HTML][HTML] Pathway-specific alterations in striatal excitability and cholinergic modulation in a SAPAP3 mouse model of compulsive motor behavior

JM Malgady, A Baez, ZB Hobel, K Jimenez, J Goldfried… - Cell reports, 2023 - cell.com
Deletion of the obsessive-compulsive disorder (OCD)-associated gene SAP90/PSD-95-
associated protein 3 (Sapap3), which encodes a postsynaptic anchoring protein at …

Dopamine oppositely modulates state transitions in striosome and matrix direct pathway striatal spiny neurons

EM Prager, DB Dorman, ZB Hobel, JM Malgady… - Neuron, 2020 - cell.com
Corticostriatal synaptic integration is partitioned among striosome (patch) and matrix
compartments of the dorsal striatum, allowing compartmentalized control of discrete aspects …

Transgenic labeling of parvalbumin-expressing neurons with tdTomato

T Kaiser, JT Ting, P Monteiro, G Feng - Neuroscience, 2016 - Elsevier
Abstract Parvalbumin (PVALB)-expressing fast-spiking interneurons subserve important
roles in many brain regions by modulating circuit function and dysfunction of these neurons …