Osteoarthritis, angiogenesis and inflammation

CS Bonnet, DA Walsh - Rheumatology, 2005 - academic.oup.com
Angiogenesis and inflammation are closely integrated processes in osteoarthritis (OA) and
may affect disease progression and pain. Inflammation can stimulate angiogenesis, and …

Angiogenesis and chronic inflammation: cause or consequence?

C Costa, J Incio, R Soares - Angiogenesis, 2007 - Springer
Evidence has been gathered regarding the association between angiogenesis and
inflammation in pathological situations. These two phenomena have long been coupled …

[PDF][PDF] Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer

JS Johansen - Dan Med Bull, 2006 - content.ugeskriftet.dk
In a search of new bone proteins, the glycoprotein YKL-40 was identified in 1989 to be
secreted in vitro in large amount by the human osteosarcoma cell line MG63. The protein …

Mathematical modelling of dynamic adaptive tumour-induced angiogenesis: clinical implications and therapeutic targeting strategies

SR McDougall, ARA Anderson… - Journal of theoretical …, 2006 - Elsevier
Angiogenesis, the growth of a network of blood vessels, is a crucial component of solid
tumour growth, linking the relatively harmless avascular growth phase and the potentially …

Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis

JAM Wessels, TWJ Huizinga, HJ Guchelaar - Rheumatology, 2008 - academic.oup.com
This review presents recent data supporting the methotrexate (MTX) mechanisms of action,
which are likely to account for its anti-proliferative and immunosuppressive effects in …

Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors

M Crowther, NJ Brown, ET Bishop… - Journal of leukocyte …, 2001 - academic.oup.com
Angiogenesis is the development of blood vessels from an existing vasculature. This
process is fundamental to both physiological wound healing and the growth of malignant …

[PDF][PDF] Cartilage and bone damage in rheumatoid arthritis

M Ostrowska, W Maśliński… - Reumatologia …, 2018 - termedia.pl
Rheumatoid arthritis (RA), which is a chronic inflammatory disease with a multifactorial
aetiology, leads to partial or permanent disability in the majority of patients. It is …

Anti-angiogenic effect of Shikonin in rheumatoid arthritis by downregulating PI3K/AKT and MAPKs signaling pathways

C Liu, L He, J Wang, Q Wang, C Sun, Y Li, K Jia… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Zicao is the dried root of Lithospermum erythrorhizon Sieb,
et Zucc, Arnebia euchroma (Royle) Johnst, or Arnebia guttata Bunge and commonly used to …

Power Doppler ultrasonography for assessment of synovitis in the metacarpophalangeal joints of patients with rheumatoid arthritis: a comparison with dynamic …

M Szkudlarek, M Court‐Payen… - … : Official Journal of …, 2001 - Wiley Online Library
Objective To evaluate the effectiveness of power Doppler ultrasonography (PDUS) for
assessing inflammatory activity in the metacarpophalangeal (MCP) joints of patients with …

Mathematical modeling of tumor-induced angiogenesis

MAJ Chaplain, SR McDougall… - Annu. Rev. Biomed …, 2006 - annualreviews.org
Angiogenesis, the growth of a network of blood vessels, is a crucial component of solid
tumor growth, linking the relatively harmless avascular and the potentially fatal vascular …