Cell and circuit complexity of the external globus pallidus
The external globus pallidus (GPe) of the basal ganglia has been underappreciated owing
to poor understanding of its cells and circuits. It was assumed that the GPe consisted of a …
to poor understanding of its cells and circuits. It was assumed that the GPe consisted of a …
A most formidable arsenal: genetic technologies for building a better mouse
The mouse is one of the most widely used model organisms for genetic study. The tools
available to alter the mouse genome have developed over the preceding decades from …
available to alter the mouse genome have developed over the preceding decades from …
Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins
Dopamine (DA) neurons in the ventral tier of the substantia nigra pars compacta (SNc)
degenerate prominently in Parkinson's disease, while those in the dorsal tier are relatively …
degenerate prominently in Parkinson's disease, while those in the dorsal tier are relatively …
Dissociable roles of pallidal neuron subtypes in regulating motor patterns
We have previously established that PV+ neurons and Npas1+ neurons are distinct neuron
classes in the external globus pallidus (GPe): they have different topographical …
classes in the external globus pallidus (GPe): they have different topographical …
Endogenous zebrafish proneural Cre drivers generated by CRISPR/Cas9 short homology directed targeted integration
We previously reported efficient precision targeted integration of reporter DNA in zebrafish
and human cells using CRISPR/Cas9 and short regions of homology. Here, we apply this …
and human cells using CRISPR/Cas9 and short regions of homology. Here, we apply this …
The characteristics of excitatory lineage differentiation and the developmental conservation in Reeler neocortex
HH Deng, SY Tong, D Shen, SQ Zhang… - Cell Proliferation, 2024 - Wiley Online Library
The majority of neocortical projection neurons are generated indirectly from radial glial cells
(RGCs) mediated by intermediate progenitor cells (IPCs) in mice. IPCs are thought to be a …
(RGCs) mediated by intermediate progenitor cells (IPCs) in mice. IPCs are thought to be a …
Application of Lineage Tracing in Central Nervous System Development and Regeneration
H Li, Y Zhuang, B Zhang, X Xu, B Liu - Molecular Biotechnology, 2024 - Springer
The central nervous system (CNS) is a complicated neural network. The origin and evolution
of functional neurons and glia cells remain unclear, as do the cellular alterations that occur …
of functional neurons and glia cells remain unclear, as do the cellular alterations that occur …
The external pallidum: think locally, act globally
The globus pallidus (GPe) of the basal ganglia has been underappreciated for decades due
to poor understanding of its cells and circuits. The advent of molecular tools has sparked a …
to poor understanding of its cells and circuits. The advent of molecular tools has sparked a …
[PDF][PDF] Dissociable roles of pallidal neuron subtypes in regulating motor patterns
Abstract (225 words) We have previously established that PV+ neurons and Npas1+
neurons are distinct neuron classes in the GPe—they have different topographical …
neurons are distinct neuron classes in the GPe—they have different topographical …
Developmental Underpinnings of Dopamine Neuron Diversity
MMP Luppi - 2023 - search.proquest.com
Dopamine (DA) neurons are involved in many brain functions, and their dysfunction is
associated with several neurodegenerative diseases. In recent years, our lab and others …
associated with several neurodegenerative diseases. In recent years, our lab and others …