Pathogenesis of human immunodeficiency virus infection

JA Levy - Microbiological reviews, 1993 - Am Soc Microbiol
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

Heterologous prime–boost vaccination

S Lu - Current opinion in immunology, 2009 - Elsevier
An effective vaccine usually requires more than one time immunization in the form of prime–
boost. Traditionally the same vaccines are given multiple times as homologous boosts. New …

Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

M Thali, JP Moore, C Furman, M Charles… - Journal of …, 1993 - Am Soc Microbiol
Interaction with the CD4 receptor enhances the exposure on the human immunodeficiency
type 1 gp120 exterior envelope glycoprotein of conserved, conformation-dependent …

[图书][B] HIV and the pathogenesis of AIDS.

JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

Protective Effects of a Live Attenuated SIV Vaccine with a Deletion in the nef Gene

MD Daniel, F Kirchhoff, SC Czajak, PK Sehgal… - Science, 1992 - science.org
Vaccine protection against the human immunodeficiency virus (HIV) and the related simian
immunodeficiency virus (SIV) in animal models is proving to be a difficult task. The difficulty …

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

S Piñol-Roma, G Dreyfuss - Nature, 1992 - nature.com
RNA polymerase II transcripts, heterogeneous nuclear RNAs (hnRNAs), associate in the
nucleus with specific proteins that bind premessenger RNA (hnRNP proteins) 1, 2 and with …

Mix-and-match COVID-19 vaccinations (heterologous boost): a review

I Garg, AB Sheikh, S Pal, R Shekhar - Infectious Disease Reports, 2022 - mdpi.com
Various safe and effective COVID-19 vaccines utilizing different platforms (mRNA,
adenovirus vector, inactivated virus-based) are available against SARS-CoV-2 infection. A …

Neutralizing antibody directed against the HIV–1 envelope glycoprotein can completely block HIV–1/SIV chimeric virus infections of macaque monkeys

R Shibata, T Igarashi, N Haigwood, A Buckler–White… - Nature medicine, 1999 - nature.com
Virus–specific antibodies protect individuals against a wide variety of viral infections 1–7. To
assess whether human immunodeficiency virus type 1 (HIV–1) envelope–specific antibodies …

Immunopathogenesis of HIV infection

G Pantaleo, AS Fauci - Annual review of microbiology, 1996 - annualreviews.org
The rate of progression of HIV disease may be substantially different among HIV-infected
individuals. Following infection of the host with any virus, the delicate balance between virus …

Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human …

P Roben, JP Moore, M Thali, J Sodroski… - Journal of …, 1994 - Am Soc Microbiol
Six recombinant human Fab fragments that were derived from the same human
immunodeficiency virus type 1 (HIV-1)-infected individual and are directed against the CD4 …