Quantitative phase imaging: recent advances and expanding potential in biomedicine

TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Quantitative phase imaging based on holography: trends and new perspectives

Z Huang, L Cao - Light: Science & Applications, 2024 - nature.com
Abstract In 1948, Dennis Gabor proposed the concept of holography, providing a pioneering
solution to a quantitative description of the optical wavefront. After 75 years of development …

Phase imaging with computational specificity (PICS) for measuring dry mass changes in sub-cellular compartments

ME Kandel, YR He, YJ Lee, THY Chen… - Nature …, 2020 - nature.com
Due to its specificity, fluorescence microscopy has become a quintessential imaging tool in
cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit …

A survey of molecular communication in cell biology: Establishing a new hierarchy for interdisciplinary applications

D Bi, A Almpanis, A Noel, Y Deng… - … Surveys & Tutorials, 2021 - ieeexplore.ieee.org
Molecular communication (MC) engineering is inspired by the use of chemical signals as
information carriers in cell biology. The biological nature of chemical signaling makes MC a …

Toward deep biophysical cytometry: prospects and challenges

KCM Lee, J Guck, K Goda, KK Tsia - Trends in Biotechnology, 2021 - cell.com
The biophysical properties of cells reflect their identities, underpin their homeostatic state in
health, and define the pathogenesis of disease. Recent leapfrogging advances in …

Emergent collective organization of bone cells in complex curvature fields

SJP Callens, D Fan, IAJ van Hengel… - Nature …, 2023 - nature.com
Individual cells and multicellular systems respond to cell-scale curvatures in their
environments, guiding migration, orientation, and tissue formation. However, it remains …

Real-time Jones phase microscopy for studying transparent and birefringent specimens

Y Jiao, ME Kandel, X Liu, W Lu, G Popescu - Optics Express, 2020 - opg.optica.org
Tissue birefringence is an intrinsic marker of potential value for cancer diagnosis.
Traditionally, birefringence properties have been studied by using intensity-based …

Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging

J Xie, H Xie, CZ Kong, T Ling - Journal of the Optical Society of …, 2024 - opg.optica.org
Quantitative phase imaging (QPI) has emerged as a powerful tool in label-free bioimaging,
in situ microstructure characterization for advanced manufacturing, and high-speed imaging …

High-resolution assessment of multidimensional cellular mechanics using label-free refractive-index traction force microscopy

M Lee, H Jeong, C Lee, MJ Lee, BR Delmo… - Communications …, 2024 - nature.com
A critical requirement for studying cell mechanics is three-dimensional assessment of
cellular shapes and forces with high spatiotemporal resolution. Traction force microscopy …

Quantitative phase imaging techniques for measuring scattering properties of cells and tissues: a review—part I

N Goswami, MA Anastasio… - Journal of biomedical …, 2024 - spiedigitallibrary.org
Significance Quantitative phase imaging (QPI) techniques offer intrinsic information about
the sample of interest in a label-free, noninvasive manner and have an enormous potential …