Humanized yeast to model human biology, disease and evolution
AH Kachroo, M Vandeloo, BM Greco… - Disease models & …, 2022 - journals.biologists.com
For decades, budding yeast, a single-cellular eukaryote, has provided remarkable insights
into human biology. Yeast and humans share several thousand genes despite …
into human biology. Yeast and humans share several thousand genes despite …
[HTML][HTML] Multifactorial theory applied to the neurotoxicity of paraquat and paraquat-induced mechanisms of developing Parkinson's disease
X Zhang, M Thompson, Y Xu - Laboratory investigation, 2016 - Elsevier
Laboratory studies involving repeated exposure to paraquat (PQ) in different animal models
can induce many of the pathological features of Parkinson's disease (PD), such as the loss …
can induce many of the pathological features of Parkinson's disease (PD), such as the loss …
Toward biotechnology in space: High-throughput instruments for in situ biological research beyond Earth
F Karouia, K Peyvan, A Pohorille - Biotechnology advances, 2017 - Elsevier
Abstract Space biotechnology is a nascent field aimed at applying tools of modern biology to
advance our goals in space exploration. These advances rely on our ability to exploit in situ …
advance our goals in space exploration. These advances rely on our ability to exploit in situ …
[HTML][HTML] Integrins in disguise-mechanosensors in Saccharomyces cerevisiae as functional integrin analogues
T Elhasi, A Blomberg - Microbial cell, 2019 - ncbi.nlm.nih.gov
The ability to sense external mechanical stimuli is vital for all organisms. Integrins are
transmembrane receptors that mediate bidirectional signalling between the extracellular …
transmembrane receptors that mediate bidirectional signalling between the extracellular …
Gearing up to handle the mosaic nature of life in the quest for orthologs
The Quest for Orthologs (QfO) is an open collaboration framework for experts in comparative
phylogenomics and related research areas who have an interest in highly accurate …
phylogenomics and related research areas who have an interest in highly accurate …
Divergence of noncoding regulatory elements explains gene–phenotype differences between human and mouse orthologous genes
Mice have been widely used as a model organism to investigate human gene–phenotype
relationships based on a conjecture that orthologous genes generally perform similar …
relationships based on a conjecture that orthologous genes generally perform similar …
[HTML][HTML] Computational strategies for cross-species knowledge transfer and translational biomedicine
Research organisms provide invaluable insights into human biology and diseases, serving
as essential tools for functional experiments, disease modeling, and drug testing. However …
as essential tools for functional experiments, disease modeling, and drug testing. However …
Technologies to Elucidate Functions of Glycans
K Furukawa, Y Ohmi, Y Kondo, Y Ohkawa… - … : Basic Science to …, 2019 - Springer
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