The mathematics of cancer: integrating quantitative models

PM Altrock, LL Liu, F Michor - Nature Reviews Cancer, 2015 - nature.com
Mathematical modelling approaches have become increasingly abundant in cancer
research. The complexity of cancer is well suited to quantitative approaches as it provides …

Cancer evolution: mathematical models and computational inference

N Beerenwinkel, RF Schwarz, M Gerstung… - Systematic …, 2015 - academic.oup.com
Cancer is a somatic evolutionary process characterized by the accumulation of mutations,
which contribute to tumor growth, clinical progression, immune escape, and drug resistance …

[HTML][HTML] Molecular ecological network analyses

Y Deng, YH Jiang, Y Yang, Z He, F Luo, J Zhou - BMC bioinformatics, 2012 - Springer
Background Understanding the interaction among different species within a community and
their responses to environmental changes is a central goal in ecology. However, defining …

The evolution of tumour phylogenetics: principles and practice

R Schwartz, AA Schäffer - Nature Reviews Genetics, 2017 - nature.com
Rapid advances in high-throughput sequencing and a growing realization of the importance
of evolutionary theory to cancer genomics have led to a proliferation of phylogenetic studies …

[HTML][HTML] An integrated insight into the relationship between soil microbial community and tobacco bacterial wilt disease

H Yang, J Li, Y Xiao, Y Gu, H Liu, Y Liang… - Frontiers in …, 2017 - frontiersin.org
The soil microbial communities play an important role in plant health, however, the
relationship between the below-ground microbiome and above-ground plant health remains …

Integrated network analysis reveals the importance of microbial interactions for maize growth

J Tao, D Meng, C Qin, X Liu, Y Liang, Y Xiao… - Applied Microbiology …, 2018 - Springer
Microbes play a critical role in soil global biogeochemical circulation and microbe–microbe
interactions have also evoked enormous interests in recent years. Utilization of green …

Multiscale modeling of inflammation-induced tumorigenesis reveals competing oncogenic and oncoprotective roles for inflammation

Y Guo, Q Nie, AL MacLean, Y Li, J Lei, S Li - Cancer research, 2017 - AACR
Chronic inflammation is a serious risk factor for cancer; however, the routes from
inflammation to cancer are poorly understood. On the basis of the processes implicated by …

[HTML][HTML] From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics

S Manrubia, JA Cuesta, J Aguirre, SE Ahnert… - Physics of Life …, 2021 - Elsevier
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is
arguably the next major missing piece in a fully predictive theory of evolution. We refer to this …

The responses and adaptations of microbial communities to salinity in farmland soils: a molecular ecological network analysis

W Zheng, D Xue, X Li, Y Deng, J Rui, K Feng… - Applied Soil Ecology, 2017 - Elsevier
Soil salinity is an increasing problem deteriorating soil fertility in degraded farmland soils.
However, the responses and adaptations of microbial communities and interactions to …

[HTML][HTML] Combining PubMed knowledge and EHR data to develop a weighted bayesian network for pancreatic cancer prediction

D Zhao, C Weng - Journal of biomedical informatics, 2011 - Elsevier
In this paper, we propose a novel method that combines PubMed knowledge and Electronic
Health Records to develop a weighted Bayesian Network Inference (BNI) model for …