We propose a novel parameter, namely, the skewness, or asymmetry, of the shape of a
receptive field to characterize two properties of hippocampal place fields. First, a majority of …

We explore the effects of short-term synaptic depression on the temporal dynamics of V1
responses to visual images by constructing a model simple cell. Synaptic depression is …

In Theory of Cortical Plasticity, Nobel Laureate Leon Cooper and his collaborators present a
systematic development of the Bienenstock, Cooper and Munro (BCM) theory of synaptic …

Is the development of orientation selectivity in visual cortex instructed by the patterns of
neural activity of input neurons? We review evidence as to the role of activity, review models …

In studies of the developing mammalian visual system, it has been axiomatic that visual
experience begins with eye-opening. Any role for neuronal activity earlier in development …

We extend previous models for separate development of ocular dominance and orientation
selectivity in cortical layer 4 by exploring conditions permitting combined organization of …

In principle, the development of sensory receptive fields in cortex could arise from
experience-independent mechanisms that have been acquired through evolution, or …

Many circuits in the mammalian brain are organized in a topographic or columnar manner.
These circuits could be activated—in ways that reveal circuit function or restore function after …

It is still an open question as to whether, and how, direction-selective neuronal responses in
primary visual cortex are generated by feedforward thalamocortical or recurrent intracortical …

We describe a possible mechanism for the formation of direction-and velocity-selective cells
in visual cortex through spike-timing dependent learning. We contrast the case where only …