Molecular mechanism and prevention strategy of chemotherapy-and radiotherapy-induced ovarian damage

S Kim, SW Kim, SJ Han, S Lee, HT Park… - International Journal of …, 2021 - mdpi.com
Fertility preservation is an emerging discipline, which is of substantial clinical value in the
care of young patients with cancer. Chemotherapy and radiation may induce ovarian …

Current and future perspectives for improving ovarian tissue cryopreservation and transplantation outcomes for cancer patients

S Lee, S Ozkavukcu, SY Ku - Reproductive Sciences, 2021 - Springer
Although advances in cancer treatment and early diagnosis have significantly improved
cancer survival rates, cancer therapies can cause serious side effects, including ovarian …

Advances in the treatment and prevention of chemotherapy-induced ovarian toxicity

HW Cho, S Lee, KJ Min, JH Hong, JY Song… - International Journal of …, 2020 - mdpi.com
Due to improvements in chemotherapeutic agents, cancer treatment efficacy and cancer
patient survival rates have greatly improved, but unfortunately gonadal damage remains a …

Review of ovarian tissue cryopreservation techniques for fertility preservation

Z Bahroudi, MR Zarnaghi, M Izadpanah… - Journal of Gynecology …, 2022 - Elsevier
Ovarian failure and ovarian malfunction are among major fertility problems in women of
reproductive age (18–35 years). It is known that various diseases, such as ovarian cancer …

Comparative effects of a calcium chelator (BAPTA-AM) and melatonin on cryopreservation-induced oxidative stress and damage in ovarian tissue

A Najafi, E Asadi, JD Benson - Scientific Reports, 2023 - nature.com
Oncology treatments cause infertility, and ovarian tissue cryopreservation and
transplantation (OTCT) is the only option for fertility preservation in prepubertal girls with …

Stepped vitrification technique for human ovarian tissue cryopreservation

ECR Leonel, A Corral, R Risco, A Camboni… - Scientific reports, 2019 - nature.com
The advantage of stepped vitrification (SV) is avoiding ice crystal nucleation, while
decreasing the toxic effects of high cryoprotectant concentrations. We aimed to test this …

Methods of ovarian tissue cryopreservation: is vitrification superior to slow freezing?—Ovarian tissue freezing methods

M Kometas, GM Christman, J Kramer… - Reproductive …, 2021 - Springer
After cancer treatment, female survivors often develop ovarian insufficiency or failure. Oocyte
and embryo freezing are well-established fertility preservation options, but cannot be …

Cryopreservation of tissues by slow-freezing using an emerging zwitterionic cryoprotectant

T Ishizaki, Y Takeuchi, K Ishibashi, N Gotoh, E Hirata… - Scientific Reports, 2023 - nature.com
Cryopreservation of tissues is a tough challenge. Cryopreservation is categorized into slow-
freezing and vitrification, and vitrification has recently been recognized as a suitable method …

Comparison of open and a novel closed vitrification system with slow freezing for human ovarian tissue cryopreservation

Y Sugishita, E Taylan, T Kawahara… - Journal of Assisted …, 2021 - Springer
Purpose To investigate the differences concerning post-thawing/warming follicle survival,
DNA damage and apoptosis in human ovarian tissues cryopreserved by slow freezing …

Vitrification versus slow freezing of human ovarian tissue: a systematic review and meta-analysis of histological outcomes

S Behl, VB Joshi, NB Larson, MC Young, M Bilal… - Journal of Assisted …, 2023 - Springer
A systematic review and meta-analysis of pertinent literature published from 2006 to January
2022 were conducted to study and compare vitrification and slow freezing, the two …