Biologically active sphingolipids are closely related to the growth, differentiation, aging, and
apoptosis of cancer cells. Some sphingolipids, such as ceramides, are favorable metabolites …

Non-alcoholic fatty liver disease (NAFLD), as one of the main causes of chronic liver disease
worldwide, encompasses a spectrum of liver conditions that are not caused by other …

With an understanding of immunity in the tumor microenvironment, immunotherapy turns out
to be a powerful tool in the clinic to treat many cancers. The strategies applied in cancer …

Purpose Ceramide is a sphingolipid metabolite that deactivates multiple oncogenic
signaling pathways and promotes cell death. In-vivo data demonstrate single-agent anti …

Nanotechnology has emerged as a promising technology in the field of hepatocellular
carcinoma (HCC), specifically in the implementation of diagnosis and treatment strategies …

Both preclinical and clinical studies have demonstrated that the modulation of gut microbiota
could be a promising strategy for enhancing antitumor immune responses and reducing …

Purpose The interaction between tumor cells and immune system in hepatocellular
carcinoma (HCC) remains unclear. Great clinical achievements have progressed in HCC …

Background Ceramides are sphingolipids that act as signaling molecules involved in
regulating cellular processes including apoptosis, proliferation, and metabolism …

Simple Summary Mammary tumors are the most prevalent type of tumor in the canine
population. C6 ceramide has been identified as an essential factor in various functions in …

Canine mammary carcinomas (CMCs) represent the most prevalent form of cancer in female
dogs, characterized by a high incidence and mortality rate. C6 ceramide is recognized for its …