Immune suppression mediated by STAT4 deficiency promotes lymphatic metastasis in HNSCC
K Anderson, N Ryan, G Volpedo, S Varikuti… - Frontiers in …, 2020 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is a prevalent form of cancer with 5-
years survival rates around 57%, and metastasis is a leading cause of mortality. Host …
years survival rates around 57%, and metastasis is a leading cause of mortality. Host …
Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures
JE Hazlewood, T Dumenil, TT Le, A Slonchak… - PLoS …, 2021 - journals.plos.org
Poxvirus systems have been extensively used as vaccine vectors. Herein a RNA-Seq
analysis of intramuscular injection sites provided detailed insights into host innate immune …
analysis of intramuscular injection sites provided detailed insights into host innate immune …
Silencing of STAT4 Protects Against Autoimmune Myocarditis by Regulating Th1/Th2 Immune Response via Inactivation of the NF-κB Pathway in Rats
YL Xue, SX Zhang, CF Zheng, YF Li, LH Zhang… - Inflammation, 2019 - Springer
Signal transducer and activator of transcription 4 (STAT4) has been implicated in the
progression of myocarditis. The aim of the current study was to investigate the role by which …
progression of myocarditis. The aim of the current study was to investigate the role by which …
Lactiplantibacillus plantarum YY‐112 ameliorates mouse immunosuppression by enhancing B/T‐cell activation and maintaining Th1/Th2 homeostasis
Y Yang, M Luo, W Zhou, W Tao, J Li, J Xing… - Food …, 2025 - Wiley Online Library
In recent years, the development of immunosuppression has become common, and
probiotics are a vital immunomodulatory strategy. This study evaluated the alleviating effect …
probiotics are a vital immunomodulatory strategy. This study evaluated the alleviating effect …
FimH as a mucosal adjuvant enhances persistent antibody response and protective efficacy of the anti-caries vaccine
ZF Liu, JL Chen, WY Li, MW Fan, YH Li - Archives of oral biology, 2019 - Elsevier
Objective To investigate whether the recombinant FimH-ST protein could modulate immune
response to anti-caries vaccine in vitro and in vivo. Design Recombinant FimH protein …
response to anti-caries vaccine in vitro and in vivo. Design Recombinant FimH protein …
'Psoriasis 1'reduces T‑lymphocyte‑mediated inflammation in patients with psoriasis by inhibiting vitamin D receptor‑mediated STAT4 inactivation
Y Gao, W Sun, X Cha, H Wang - … Journal of Molecular …, 2020 - spandidos-publications.com
Psoriasis is an immune‑mediated dermatosis characterized by T‑lymphocyte‑mediated
epidermal hyperplasia, for which there are currently no effective clinical treatments.'Psoriasis …
epidermal hyperplasia, for which there are currently no effective clinical treatments.'Psoriasis …
Vaccine adjuvants CpG (oligodeoxynucleotides ODNs), MPL (3-O-deacylated monophosphoryl lipid A) and naloxone-enhanced Th1 immune response to the …
S Nazeri, S Zakeri, AA Mehrizi, ND Djadid… - Medical microbiology …, 2018 - Springer
Despite considerable efforts toward vaccine development over decades, there is no
available effective vaccine against Plasmodium vivax. Thrombospondin-related adhesive …
available effective vaccine against Plasmodium vivax. Thrombospondin-related adhesive …
[HTML][HTML] 单磷酰脂A 佐剂的热原控制方法研究
裴宇盛， 蔡彤， 陈晨， 高华 - 2020 - html.rhhz.net
目的研究建立单磷酰脂A 佐剂的热原控制方法. 方法对2 批不同来源的单磷酰脂A
分别采用细菌内毒素检查法, TLR2 高表达HEK 细胞和TLR4 高表达HEK 细胞报告基因法进行了 …
分别采用细菌内毒素检查法, TLR2 高表达HEK 细胞和TLR4 高表达HEK 细胞报告基因法进行了 …
[PDF][PDF] Factors regulating Th17 cells: a review
R Seki, K Nishizawa - Biomedical Research and Clinical Practice, 2016 - researchmap.jp
This article aims to provide a broad coverage of over 300 studies on T helper 17 (Th17) cells
published mainly between 2011 and 2016, with a focus on factors negatively regulating …
published mainly between 2011 and 2016, with a focus on factors negatively regulating …
[HTML][HTML] rs16833431 位点多态性与淋巴细胞主动免疫治疗URSA 后妊娠结局的相关性探讨
贺凌云， 万志勇 - 新医学, 2018 - xinyixue.cn
目的探讨信号转导与转录激活因子4 (STAT4) 基因rs16833431 位点基因多态性与淋巴细胞主动
免疫治疗原因不明复发性自然流产(URSA) 后妊娠结局的相关性. 方法采用配偶或者第三方亲属 …
免疫治疗原因不明复发性自然流产(URSA) 后妊娠结局的相关性. 方法采用配偶或者第三方亲属 …