TNAP is a novel regulator of cardiac fibrosis after myocardial infarction by mediating TGF-β/Smads and ERK1/2 signaling pathways

X Cheng, L Wang, X Wen, L Gao, G Li, G Chang… - …, 2021 - thelancet.com
Background Cardiac fibrosis is the most important pathogenesis leading to cardiac
remodeling and heart failure after myocardial infarction (MI). Tissue nonspecific alkaline …

[HTML][HTML] Adverse neurobehavioral changes with reduced blood and brain cholinesterase activities in mice treated with statins

RF Al-Shalchi, FK Mohammad - Veterinary World, 2024 - ncbi.nlm.nih.gov
Materials and Methods: Two hours after vehicle (control) or statin dosing at 250, 500, 750, or
1000 mg/kg orally, each mouse was subjected to 5 min open-field activity, negative geotaxis …

A potential association between Toxoplasma gondii infection and schizophrenia in mouse models

T Wang, Z Tang, J Li, X Li, X Wang, Z Zhao - Experimental parasitology, 2013 - Elsevier
Schizophrenia is a serious neuropsychiatric disease of uncertain etiology, which causes
human mental disorder and affects about 1% of the population. In recently years, some …

Development and validation of a multi-residue screening method for veterinary drugs, their metabolites and pesticides in meat using liquid chromatography-tandem …

H Wei, Y Tao, D Chen, S Xie, Y Pan, Z Liu… - Food Additives & …, 2015 - Taylor & Francis
A rapid multi-residue screening method that includes 128 veterinary anti-parasitic drugs and
metabolites in meat of chicken, porcine and bovine has been developed. The scope of the …

Activation of calcium-sensing receptors in the basolateral nucleus of the amygdala inhibits food intake and induces anxiety-depressive-like emotions via dopamine …

Y Guo, Z Jiang, T Jin, J Huang, X Sun - Behavioural Brain Research, 2023 - Elsevier
The calcium-sensing receptor (CaSR) is abundantly expressed in gastrointestinal mucosa
and participates in the regulation of feeding by affecting hormone secretion. Studies have …

A dual validation approach to detect anthelmintic residues in bovine liver over an extended concentration range

B Kinsella, M Whelan, H Cantwell, M McCormack… - Talanta, 2010 - Elsevier
This paper describes a method for the detection and quantification of 38 residues of the most
widely used anthelmintics (including 26 veterinary drugs belonging to the benzimidazole …

Tetramisole and levamisole suppress neuronal activity independently from their inhibitory action on tissue non-specific alkaline phosphatase in mouse cortex

LG Nowak, B Rosay, D Czégé, C Fonta - Neuronal tissue-nonspecific …, 2015 - Springer
Tissue non-specific alkaline phosphatase (TNAP) may be involved in the synthesis of GABA
and adenosine, which are the main inhibitory neurotransmitters in cortex. We explored this …

Calculation of 95% confidence interval of the median lethal dose determined by the up-and-down procedure: a letter to editor

FK Mohammad - Journal of Ideas in Health, 2022 - jidhealth.com
Calculation of 95% confidence interval of the median lethal dose determined by the up-and-down
procedure: a letter to editor Page 1 https://doi.org/10.47108/jidhealth.Vol5.Iss3.233 …

Vinylic telluride derivatives as promising pharmacological compounds with low toxicity

VC Borges, L Savegnago, S Pinton… - Journal of Applied …, 2008 - Wiley Online Library
The aim of the present study was to evaluate pharmacological and toxicological properties
of (Z)‐2‐(methylthio)‐1‐(butyltelluro)‐1‐phenylethene 1a,(Z)‐1‐(4‐methylphenylsulfonyl)‐2 …

Effect of memantine hydrochloride on cisplatin-induced neurobehavioral toxicity in mice

NA Salih, BK Al-Baggou - Acta Neurologica Belgica, 2020 - Springer
Cisplatin is an anticancer agent widely used in the treatment of malignant tumors. One of the
major adverse effects of cisplatin is its neurotoxicity. Memantine, an uncompetitive N-methyl …