Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Loss of skeletal integrity during ageing and disease is associated with an imbalance in the
opposing actions of osteoblasts and osteoclasts. Here we show that intrinsic ageing of …

The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

In the early stage of osteoarthritis (OA), cartilage degradation in the surface region leads to
superficial cartilage defect. However, enhancing the regeneration of cartilage defect remains …

Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

The inappropriate regenerated fibrous cartilage and subchondral bone of the injured
chondral defect ultimately cause degeneration of the regenerated cartilage, which …

Intra-articular injection of therapeutics is an effective strategy for treating osteoarthritis (OA),
but it is hindered by rapid drug diffusion, thereby necessitating high-frequency injections …

MicroRNAs (miRNAs) regulate several physiological and pathological processes involved in
various diseases, including osteoarthritis (OA). OA is the most common global …

With the growing demand for next-generation health care, the integration of electronic
components into implantable medical devices (IMDs) has become a vital factor in achieving …