Gene expression profiling in human neurodegenerative disease
Transcriptome study in neurodegenerative disease has advanced considerably in the past 5
years. Increasing scientific rigour and improved analytical tools have led to more …
years. Increasing scientific rigour and improved analytical tools have led to more …
Prognostic biomarkers in uveal melanoma: The status quo, recent advances and future directions
NJ Lamas, A Martel, S Nahon-Estève, S Goffinet… - Cancers, 2021 - mdpi.com
Simple Summary Although rare, uveal melanoma (UM) is the most common cancer that
develops inside adult eyes. The prognosis is poor, since 50% of patients will develop lethal …
develops inside adult eyes. The prognosis is poor, since 50% of patients will develop lethal …
Colon cancer diagnosis and staging classification based on machine learning and bioinformatics analysis
Y Su, X Tian, R Gao, W Guo, C Chen, C Chen… - Computers in biology …, 2022 - Elsevier
Advanced metastasis of colon cancer makes it more difficult to treat colon cancer. Finding
the markers of colon cancer (Colon Cancer) can diagnose the stage of cancer in time and …
the markers of colon cancer (Colon Cancer) can diagnose the stage of cancer in time and …
[HTML][HTML] Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects
Using induced pluripotent stem cells (iPSCs) to understand the mechanisms of neurological
disease holds great promise; however, there is a lack of well-curated lines from a large array …
disease holds great promise; however, there is a lack of well-curated lines from a large array …
Marked seasonal variation in structure and function of gut microbiota in forest and alpine musk deer
F Jiang, H Gao, W Qin, P Song, H Wang… - Frontiers in …, 2021 - frontiersin.org
Musk deer (Moschus spp.) is a globally endangered species due to excessive hunting and
habitat fragmentation. Captive breeding of musk deer can efficiently relieve the hunting …
habitat fragmentation. Captive breeding of musk deer can efficiently relieve the hunting …
Strategies for aggregating gene expression data: the collapseRows R function
Background Genomic and other high dimensional analyses often require one to summarize
multiple related variables by a single representative. This task is also variously referred to as …
multiple related variables by a single representative. This task is also variously referred to as …
Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence
Alcohol abuse causes widespread changes in gene expression in human brain, some of
which contribute to alcohol dependence. Previous microarray studies identified individual …
which contribute to alcohol dependence. Previous microarray studies identified individual …
Gene networks specific for innate immunity define post-traumatic stress disorder
The molecular factors involved in the development of Post-Traumatic Stress Disorder
(PTSD) remain poorly understood. Previous transcriptomic studies investigating the …
(PTSD) remain poorly understood. Previous transcriptomic studies investigating the …
Principal component analysis based methods in bioinformatics studies
In analysis of bioinformatics data, a unique challenge arises from the high dimensionality of
measurements. Without loss of generality, we use genomic study with gene expression …
measurements. Without loss of generality, we use genomic study with gene expression …
[HTML][HTML] Massive transcriptome sequencing of human spinal cord tissues provides new insights into motor neuron degeneration in ALS
ALS is a devastating and debilitating human disease characterized by the progressive death
of upper and lower motor neurons. Although much effort has been made to elucidate …
of upper and lower motor neurons. Although much effort has been made to elucidate …