Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

One of the challenges posed by current antibacterial therapy is that the expanded and
massive use of antibiotics endows bacteria with the ability to resist almost all kinds of …

Clinical treatment of pathogenic infection has emerged as a growing challenge in global
public health. Such treatment is currently limited to antibiotics, but abuse of antibiotics have …

Conspectus Bacterial infection continues to be a growing global health problem with the
most widely accepted treatment paradigms restricted to antibiotics. However, antibiotics …

Promoting rapid healing of diabetic wounds caused by hyperglycemia, bacterial infection,
and chronic inflammation is a global challenge. To address this issue, we design and …

Extracellular polymeric substances (EPS) are present both outside of the cells and in the
interior of microbial aggregates, and account for a main component in microbial aggregates …

Implant-related infections (IRIs) are a serious complication after orthopedic surgery,
especially when a biofilm develops and establishes physical and chemical barriers …

Biofilm formation is a main challenge in treatment of bone-implant-associated infections,
resulting in tolerance to immune system and antibiotics. However, smart non-surgical or non …

The emergence of multi-drug resistance makes bacterial infection a major threat to public
health and economy. The formation of bacterial biofilms is one of the main reasons of …

Notorious bacterial biofilms are becoming severe threats to public health worldwide. As the
important component in biofilm extracellular polymeric substances (EPS), extracellular DNA …