Motor proteins

HL Sweeney, ELF Holzbaur - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Myosin motors power movements on actin filaments, whereas dynein and kinesin motors
power movements on microtubules. The mechanisms of these motor proteins differ, but, in …

Molecular motors

M Schliwa, G Woehlke - Nature, 2003 - nature.com
Life implies movement. Most forms of movement in the living world are powered by tiny
protein machines known as molecular motors. Among the best known are motors that use …

[HTML][HTML] The molecular basis for sarcomere organization in vertebrate skeletal muscle

Z Wang, M Grange, T Wagner, AL Kho, M Gautel… - Cell, 2021 - cell.com
Sarcomeres are force-generating and load-bearing devices of muscles. A precise molecular
picture of how sarcomeres are built underpins understanding their role in health and …

Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase

R Yasuda, H Noji, M Yoshida, K Kinosita Jr, H Itoh - Nature, 2001 - nature.com
The enzyme F1-ATPase has been shown to be a rotary motor in which the central γ-subunit
rotates inside the cylinder made of α3β3 subunits. At low ATP concentrations, the motor …

[HTML][HTML] Structure of the rigor actin-tropomyosin-myosin complex

E Behrmann, M Müller, PA Penczek, HG Mannherz… - Cell, 2012 - cell.com
Regulation of myosin and filamentous actin interaction by tropomyosin is a central feature of
contractile events in muscle and nonmuscle cells. However, little is known about molecular …

Hypertrophic and dilated cardiomyopathy: four decades of basic research on muscle lead to potential therapeutic approaches to these devastating genetic diseases

JA Spudich - Biophysical journal, 2014 - cell.com
With the advent of technologies to obtain the complete sequence of the human genome in a
cost-effective manner, this decade and those to come will see an exponential increase in our …

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes

L Alamo, JS Ware, A Pinto, RE Gillilan, JG Seidman… - elife, 2017 - elifesciences.org
Cardiac β-myosin variants cause hypertrophic (HCM) or dilated (DCM) cardiomyopathy by
disrupting sarcomere contraction and relaxation. The locations of variants on isolated …

Structural and functional insights into the myosin motor mechanism

HL Sweeney, A Houdusse - Annual review of biophysics, 2010 - annualreviews.org
The general structural features of the motor region of myosin superfamily members are now
well established, as is a subset of the structural and kinetic transitions of the actin-myosin …

Force generation by myosin motors: a structural perspective

J Robert-Paganin, O Pylypenko, C Kikuti… - Chemical …, 2019 - ACS Publications
Generating force and movement is essential for the functions of cells and organisms. A
variety of molecular motors that can move on tracks within cells have evolved to serve this …

[图书][B] Scallops: biology, ecology, aquaculture, and fisheries

SE Shumway, GJ Parsons - 2016 - books.google.com
Scallops: Biology, Ecology, Aquaculture and Fisheries, Third Edition, continues its history as
the definitive resource on scallops, covering all facets of scallop biology, including anatomy …