Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

Background Critical examination of the quality and validity of available allergic rhinitis (AR)
literature is necessary to improve understanding and to appropriately translate this …

Allergic rhinitis (AR) is a global health problem with increasing prevalence and association
with an enormous medical and socioeconomic burden. New recognition of immune cells …

We have prepared this document,“Sublingual Immunotherapy: World Allergy Organization
Position Paper 2013 Update”, according to the evidence-based criteria, revising and …

Asthma is the most common chronic lower respiratory disease in childhood throughout the
world. Several guidelines and/or consensus documents are available to support medical …

Group 2 innate lymphoid cells (ILC2s) in the lung are stimulated by inhaled allergens. ILC2s
do not directly recognize allergens but they are stimulated by cytokines including interleukin …

Allergy immunotherapy (AIT) is an effective treatment for allergic asthma and rhinitis, as well
as venom-induced anaphylaxis. In addition to reducing symptoms, AIT can change the …

Clinical indications for allergen immunotherapy (AIT) in respiratory and Hymenoptera venom
allergy are well established; however, clinical contraindications to AIT are not always well …

Allergen immunotherapy (AIT) has been used to treat allergic disease since the early 1900s.
Despite numerous clinical trials and meta-analyses proving AIT efficacious, it remains …