Paracoccidioides-host Interaction: An Overview on Recent Advances in the Paracoccidioidomycosis

HC De Oliveira, PA Assato, CM Marcos… - Frontiers in …, 2015 - frontiersin.org
Paracoccidioides brasiliensis and P. lutzii are etiologic agents of paracoccidioidomycosis
(PCM), an important endemic mycosis in Latin America. During its evolution, these fungi …

The Trojan Horse Model in Paracoccidioides: A Fantastic Pathway to Survive Infecting Human Cells

G Giusiano - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
Paracoccidioidomycosis (PCM) is the most relevant systemic endemic mycosis limited to
Latin American countries. The etiological agents are thermally dimorphic species of the …

Clinical features and genetic background of the sympatric species Paracoccidioides brasiliensis and Paracoccidioides americana

PM De Macedo, MM Teixeira, BM Barker… - PLoS neglected …, 2019 - journals.plos.org
Introduction The agents of paracoccidioidomycosis, historically identified as
Paracoccidioides brasiliensis, are in fact different phylogenetic species. This study aims to …

A unique cell wall synthetic response evoked by glucosamine determines pathogenicity-associated fungal cellular differentiation

P Hu, H Ding, L Shen, GJ He, H Liu, X Tian, C Tao… - PLoS …, 2021 - journals.plos.org
The yeast-to-hypha transition is tightly associated with pathogenicity in many human
pathogenic fungi, such as the model fungal pathogen Cryptococcus neoformans, which is …

New insights into a complex fungal pathogen: the case of Paracoccidioides spp.

A Gonzalez, O Hernandez - Yeast, 2016 - Wiley Online Library
Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with
Paracoccidioides brasiliensis and P. lutzii being the causal agents of this disorder. Several …

Transcriptomic crosstalk between fungal invasive pathogens and their host cells: opportunities and challenges for next-generation sequencing methods

FJ Enguita, MC Costa, AM Fusco-Almeida… - Journal of Fungi, 2016 - mdpi.com
Fungal invasive infections are an increasing health problem. The intrinsic complexity of
pathogenic fungi and the unmet clinical need for new and more effective treatments requires …

[HTML][HTML] iTRAQ-based proteomic analysis of Paracoccidioides brasiliensis in response to hypoxia

LN Oliveira, P de Sousa Lima, DS Araújo… - Microbiological …, 2021 - Elsevier
Aerobic organisms require oxygen for energy. In the course of the infection, adaptation to
hypoxia is crucial for survival of human pathogenic fungi. Members of the Paracoccidioides …

rPbPga1 from Paracoccidioides brasiliensis Activates Mast Cells and Macrophages via NFkB

CXR Valim, EZM da Silva, MA Assis… - PLoS Neglected …, 2015 - journals.plos.org
Background The fungus Paracoccidioides brasiliensis is the leading etiological agent of
paracoccidioidomycosis (PCM), a systemic granulomatous disease that typically affects the …

Shrinking Daughters: Rlm1-Dependent G1/S Checkpoint Maintains Saccharomyces cerevisiae Daughter Cell Size and Viability

S Piccirillo, D Neog, D Spade, JD Van Horn… - Genetics, 2017 - academic.oup.com
How do cells ensure everything is set for cell division before they start the process? Piccirillo
et al. demonstrate that a checkpoint in budding.... The Rlm1 transcription factor is a target of …

Large-scale genomic analyses of in vitro yeast-mycelium dimorphism in human, insect and plant pathogenic fungi: From ESTs to RNAseq experiments

M Nigg, L Bernier - Fungal biology reviews, 2017 - Elsevier
Yeast-mycelium fungal dimorphism is a complex trait studied for many years, particularly in
pathogenic fungi for which the morphological switch is often associated with virulence. It is a …