MicroRNA 122 affects both the initiation and the maintenance of hepatitis C virus infections
M Panigrahi, PA Thibault, JA Wilson - Journal of Virology, 2022 - Am Soc Microbiol
ABSTRACT A liver-specific microRNA, miR-122, anneals to the hepatitis C virus (HCV)
genomic 5′ terminus and is essential for virus replication in cell culture. However …
genomic 5′ terminus and is essential for virus replication in cell culture. However …
Regulation of hepatitis C virus genome replication by Xrn1 and microRNA-122 binding to individual sites in the 5′ untranslated region
PA Thibault, A Huys, Y Amador-Cañizares… - Journal of …, 2015 - Am Soc Microbiol
ABSTRACT miR-122 is a liver-specific microRNA (miRNA) that binds to two sites (S1 and
S2) on the 5′ untranslated region (UTR) of the hepatitis C virus (HCV) genome and …
S2) on the 5′ untranslated region (UTR) of the hepatitis C virus (HCV) genome and …
Signature molecules expressed differentially in a liver disease stage-specific manner by HIV-1 and HCV co-infection
To elucidate HIV-1 co-infection-induced acceleration of HCV liver disease and identify stage-
specific molecular signatures, we applied a new high-resolution molecular screen, the …
specific molecular signatures, we applied a new high-resolution molecular screen, the …
[PDF][PDF] miR-122-independent propagation of Hepatitis C Virus: Understanding the underlying mechanism through characterization of viral replication.
M Panigrahi - 2021 - harvest.usask.ca
Hepatitis C Virus (HCV) is a serious global health problem, infecting almost 3% of the
world's population. Infection with the Hepatitis C virus (HCV) leads to chronic liver infections …
world's population. Infection with the Hepatitis C virus (HCV) leads to chronic liver infections …
Exploring genetic and physical aspects of Hepatitis C Virus non-structural proteins involved in the formation of the replication complex
R Gomes - 2017 - eprints.soton.ac.uk
Hepatitis C Virus (HCV) is the causative agent of Hepatitis C, a chronic liver disease that is
responsible for significant morbidity and mortality throughout the world. Replication of the …
responsible for significant morbidity and mortality throughout the world. Replication of the …
Genetic and molecular technologies to optimise novel vaccines for Hepatitis C virus infection
L Swadling - 2015 - ora.ox.ac.uk
Analysis of the immune response during spontaneous clearance and protection upon
reinfection with hepatitis C (HCV) has highlighted the importance of T-cells in the control of …
reinfection with hepatitis C (HCV) has highlighted the importance of T-cells in the control of …
[PDF][PDF] Exploiting and exploring the interactions between microRNA-122 and Hepatitis C virus
P Thibault - 2014 - harvest.usask.ca
Hepatitis C virus (HCV) is a single-stranded plus-sense RNA virus that is transmitted by
blood-to-blood contact, and infects the human liver. HCV has a unique dependence on the …
blood-to-blood contact, and infects the human liver. HCV has a unique dependence on the …