Whole-brain profiling of cells and circuits in mammals by tissue clearing and light-sheet microscopy
Tissue clearing and light-sheet microscopy have a 100-year-plus history, yet these fields
have been combined only recently to facilitate novel experiments and measurements in …
have been combined only recently to facilitate novel experiments and measurements in …
Pathology imaging informatics for quantitative analysis of whole-slide images
Objectives With the objective of bringing clinical decision support systems to reality, this
article reviews histopathological whole-slide imaging informatics methods, associated …
article reviews histopathological whole-slide imaging informatics methods, associated …
A platform for brain-wide imaging and reconstruction of individual neurons
The structure of axonal arbors controls how signals from individual neurons are routed
within the mammalian brain. However, the arbors of very few long-range projection neurons …
within the mammalian brain. However, the arbors of very few long-range projection neurons …
The logic of single-cell projections from visual cortex
Neocortical areas communicate through extensive axonal projections, but the logic of
information transfer remains poorly understood, because the projections of individual …
information transfer remains poorly understood, because the projections of individual …
Augmented reality technology using Microsoft HoloLens in anatomic pathology
MG Hanna, I Ahmed, J Nine… - … of pathology & …, 2018 - meridian.allenpress.com
Context Augmented reality (AR) devices such as the Microsoft HoloLens have not been well
used in the medical field. Objective To test the HoloLens for clinical and nonclinical …
used in the medical field. Objective To test the HoloLens for clinical and nonclinical …
Serial two-photon tomography for automated ex vivo mouse brain imaging
T Ragan, LR Kadiri, KU Venkataraju, K Bahlmann… - Nature …, 2012 - nature.com
Here we describe an automated method, named serial two-photon (STP) tomography, that
achieves high-throughput fluorescence imaging of mouse brains by integrating two-photon …
achieves high-throughput fluorescence imaging of mouse brains by integrating two-photon …
Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates
Delivering genes to and across the brain vasculature efficiently and specifically across
species remains a critical challenge for addressing neurological diseases. We have evolved …
species remains a critical challenge for addressing neurological diseases. We have evolved …
Precise cerebral vascular atlas in stereotaxic coordinates of whole mouse brain
Understanding amazingly complex brain functions and pathologies requires a complete
cerebral vascular atlas in stereotaxic coordinates. Making a precise atlas for cerebral …
cerebral vascular atlas in stereotaxic coordinates. Making a precise atlas for cerebral …
[HTML][HTML] Cooperative thalamocortical circuit mechanism for sensory prediction errors
The brain functions as a prediction machine, utilizing an internal model of the world to
anticipate sensations and the outcomes of our actions. Discrepancies between expected …
anticipate sensations and the outcomes of our actions. Discrepancies between expected …
Micro-optical sectioning tomography to obtain a high-resolution atlas of the mouse brain
The neuroanatomical architecture is considered to be the basis for understanding brain
function and dysfunction. However, existing imaging tools have limitations for brainwide …
function and dysfunction. However, existing imaging tools have limitations for brainwide …